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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1831 1
1839 1
1853 1
1856 1
1860 1
1876 2
1886 2
1887 4
1888 2
1889 3
1890 3
1891 2
1892 4
1893 2
1894 3
1895 2
1896 2
1897 4
1898 3
1899 8
1900 3
1902 7
1905 1
1908 2
1909 4
1910 5
1911 1
1912 4
1913 13
1914 10
1915 11
1916 7
1917 7
1918 2
1919 8
1920 12
1921 10
1922 3
1923 2
1924 3
1925 4
1926 1
1927 1
1928 2
1929 1
1930 1
1931 5
1932 1
1934 2
1935 7
1936 3
1937 2
1938 2
1940 1
1943 1
1944 1
1945 7
1946 7
1947 11
1948 12
1949 12
1950 6
1951 10
1952 6
1953 10
1954 12
1955 9
1956 8
1957 3
1958 14
1959 15
1960 12
1961 13
1962 15
1963 23
1964 21
1965 27
1966 42
1967 50
1968 52
1969 54
1970 74
1971 71
1972 68
1973 71
1974 74
1975 143
1976 151
1977 200
1978 224
1979 245
1980 242
1981 297
1982 403
1983 459
1984 568
1985 599
1986 693
1987 761
1988 866
1989 977
1990 1254
1991 1354
1992 1600
1993 1796
1994 2022
1995 2292
1996 2886
1997 3164
1998 3980
1999 5320
2000 8866
2001 12165
2002 13695
2003 17299
2004 18664
2005 20836
2006 20596
2007 20168
2008 19883
2009 18722
2010 20198
2011 20610
2012 21871
2013 24830
2014 30060
2015 32483
2016 33260
2017 32327
2018 32215
2019 31879
2020 34467
2021 36555
2022 35476
2023 32283
2024 10854

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565,080 results

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Page 1
DEAD-Box RNA Helicases and Genome Stability.
Cargill M, Venkataraman R, Lee S. Cargill M, et al. Genes (Basel). 2021 Sep 23;12(10):1471. doi: 10.3390/genes12101471. Genes (Basel). 2021. PMID: 34680866 Free PMC article. Review.
DEAD-box RNA helicases are important regulators of RNA metabolism and have been implicated in the development of cancer. ...Finally, we summarized the pathological and therapeutic relationship between DEAD-box RNA helicases and cancer with respect to their novel rol …
DEAD-box RNA helicases are important regulators of RNA metabolism and have been implicated in the development of cancer. ...Finally, …
The Biology of F-box Proteins: The SCF Family of E3 Ubiquitin Ligases.
Nguyen KM, Busino L. Nguyen KM, et al. Adv Exp Med Biol. 2020;1217:111-122. doi: 10.1007/978-981-15-1025-0_8. Adv Exp Med Biol. 2020. PMID: 31898225 Review.
F-box proteins function as substrate adaptors for the S-phase kinase-associated protein 1 (SKP1)-cullin 1 (CUL1)-F-box protein (SCF) ubiquitin ligase complexes, which mediate the proteasomal degradation of a diverse range of regulatory proteins. 20 years since the F …
F-box proteins function as substrate adaptors for the S-phase kinase-associated protein 1 (SKP1)-cullin 1 (CUL1)-F-box protein …
DExH/D-box helicases at the frontline of intrinsic and innate immunity against viral infections.
Bonaventure B, Goujon C. Bonaventure B, et al. J Gen Virol. 2022 Aug;103(8). doi: 10.1099/jgv.0.001766. J Gen Virol. 2022. PMID: 36006669 Review.
However, other DExH/D-box helicases have recurrently been highlighted as direct antiviral effectors or as positive regulators of innate immune activation. ...Hence, DExH/D-box helicases appear to form a multilayer network of primary and secondary factors involved in …
However, other DExH/D-box helicases have recurrently been highlighted as direct antiviral effectors or as positive regulators of inna …
F-box only protein 9 and its role in cancer.
Hussain S, Dong J, Ma X, Li J, Chen S, Clement A, Liu H. Hussain S, et al. Mol Biol Rep. 2022 Feb;49(2):1537-1544. doi: 10.1007/s11033-021-07057-7. Epub 2022 Jan 13. Mol Biol Rep. 2022. PMID: 35025031 Review.
The F-box proteins (FBP), substrate recognition subunit of the SCF (Skp1-Cullin1-F-box protein complex) E3 ligase, play important roles in the ubiquitylation and subsequent degradation of the target proteins from several cellular processes. ...Targeting F-box …
The F-box proteins (FBP), substrate recognition subunit of the SCF (Skp1-Cullin1-F-box protein complex) E3 ligase, play import …
Inhibitors Targeting the F-BOX Proteins.
Naseem Y, Zhang C, Zhou X, Dong J, Xie J, Zhang H, Agboyibor C, Bi Y, Liu H. Naseem Y, et al. Cell Biochem Biophys. 2023 Dec;81(4):577-597. doi: 10.1007/s12013-023-01160-1. Epub 2023 Aug 25. Cell Biochem Biophys. 2023. PMID: 37624574 Review.
Any significant mutation in F-box protein-mediated proteolysis can cause human malformations. ...To target F-box proteins and their associated signaling pathways for cancer treatment, researchers have developed thousands of F-box inhibitors. ...
Any significant mutation in F-box protein-mediated proteolysis can cause human malformations. ...To target F-box proteins and …
From unwinding to clamping - the DEAD box RNA helicase family.
Linder P, Jankowsky E. Linder P, et al. Nat Rev Mol Cell Biol. 2011 Jul 22;12(8):505-16. doi: 10.1038/nrm3154. Nat Rev Mol Cell Biol. 2011. PMID: 21779027 Review.
RNA helicases of the DEAD box family are present in all eukaryotic cells and in many bacteria and Archaea. These highly conserved enzymes are required for RNA metabolism from transcription to degradation and are therefore important players in gene expression. DEAD box …
RNA helicases of the DEAD box family are present in all eukaryotic cells and in many bacteria and Archaea. These highly conserved enz …
DExD/H-box helicases: multifunctional regulators in antiviral innate immunity.
Su C, Tang YD, Zheng C. Su C, et al. Cell Mol Life Sci. 2021 Dec 15;79(1):2. doi: 10.1007/s00018-021-04072-6. Cell Mol Life Sci. 2021. PMID: 34910251 Free PMC article. Review.
DExD/H-box helicases play critical roles in multiple cellular processes, including transcription, cellular RNA metabolism, translation, and infections. ...Besides the prominent regulatory roles, there is increasing attention on their functions as nucleic acid sensors invol …
DExD/H-box helicases play critical roles in multiple cellular processes, including transcription, cellular RNA metabolism, translatio …
DEAD-Box Helicases: Sensors, Regulators, and Effectors for Antiviral Defense.
Taschuk F, Cherry S. Taschuk F, et al. Viruses. 2020 Feb 5;12(2):181. doi: 10.3390/v12020181. Viruses. 2020. PMID: 32033386 Free PMC article. Review.
DEAD-box helicases are a large family of conserved RNA-binding proteins that belong to the broader group of cellular DExD/H helicases. Members of the DEAD-box helicase family have roles throughout cellular RNA metabolism from biogenesis to decay. ...
DEAD-box helicases are a large family of conserved RNA-binding proteins that belong to the broader group of cellular DExD/H helicases …
Role of F-box E3-ubiquitin ligases in plant development and stress responses.
Saxena H, Negi H, Sharma B. Saxena H, et al. Plant Cell Rep. 2023 Jul;42(7):1133-1146. doi: 10.1007/s00299-023-03023-8. Epub 2023 May 17. Plant Cell Rep. 2023. PMID: 37195503 Review.
F-box E3-ubiquitin ligases regulate critical biological processes in plant development and stress responses. ...The diverse and most prominent protein family among eukaryotes, F-box proteins, are a vital component of the multi-subunit SCF (Skp1-Cullin 1-F-box …
F-box E3-ubiquitin ligases regulate critical biological processes in plant development and stress responses. ...The diverse and most …
T-Box Genes in Drosophila Mesoderm Development.
Reim I, Frasch M, Schaub C. Reim I, et al. Curr Top Dev Biol. 2017;122:161-193. doi: 10.1016/bs.ctdb.2016.06.003. Epub 2016 Jul 30. Curr Top Dev Biol. 2017. PMID: 28057263 Review.
In Drosophila there are eight genes encoding transcription factors of the T-box family, which are known to exert a variety of crucial developmental functions during ectodermal patterning processes, neuronal cell specification, mesodermal tissue development, and the develop …
In Drosophila there are eight genes encoding transcription factors of the T-box family, which are known to exert a variety of crucial …
565,080 results
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