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Items: 1 to 20 of 78

1.

Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila.

Guida MC, Birse RT, Dall'Agnese A, Toto PC, Diop SB, Mai A, Adams PD, Puri PL, Bodmer R.

Nat Commun. 2019 Jan 14;10(1):193. doi: 10.1038/s41467-018-08128-3.

2.

SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila.

Zanon A, Kalvakuri S, Rakovic A, Foco L, Guida M, Schwienbacher C, Serafin A, Rudolph F, Trilck M, Grünewald A, Stanslowsky N, Wegner F, Giorgio V, Lavdas AA, Bodmer R, Pramstaller PP, Klein C, Hicks AA, Pichler I, Philip S.

Hum Mol Genet. 2018 Nov 29. doi: 10.1093/hmg/ddy408. [Epub ahead of print] No abstract available.

PMID:
30517638
3.

As time flies by: Investigating cardiac aging in the short-lived Drosophila model.

Blice-Baum AC, Guida MC, Hartley PS, Adams PD, Bodmer R, Cammarato A.

Biochim Biophys Acta Mol Basis Dis. 2018 Nov 27. pii: S0925-4439(18)30469-1. doi: 10.1016/j.bbadis.2018.11.010. [Epub ahead of print] Review.

PMID:
30496794
4.

A homozygous KAT2B variant modulates the clinical phenotype of ADD3 deficiency in humans and flies.

Gonçalves S, Patat J, Guida MC, Lachaussée N, Arrondel C, Helmstädter M, Boyer O, Gribouval O, Gubler MC, Mollet G, Rio M, Charbit M, Bole-Feysot C, Nitschke P, Huber TB, Wheeler PG, Haynes D, Juusola J, Billette de Villemeur T, Nava C, Afenjar A, Keren B, Bodmer R, Antignac C, Simons M.

PLoS Genet. 2018 May 16;14(5):e1007386. doi: 10.1371/journal.pgen.1007386. eCollection 2018 May. Erratum in: PLoS Genet. 2018 Oct 26;14(10):e1007748.

5.

Ceramide-Protein Interactions Modulate Ceramide-Associated Lipotoxic Cardiomyopathy.

Walls SM, Cammarato A, Chatfield DA, Ocorr K, Harris GL, Bodmer R.

Cell Rep. 2018 Mar 6;22(10):2702-2715. doi: 10.1016/j.celrep.2018.02.034.

6.

The bHLH Protein Nulp1 is Essential for Femur Development Via Acting as a Cofactor in Wnt Signaling in Drosophila.

Zeng Q, Wan Y, Zhu P, Zhao M, Jiang F, Chen J, Tang M, Zhu X, Li Y, Zha H, Wang Y, Hu M, Mo X, Zhang Y, Chen Y, Chen Y, Ye X, Bodmer R, Ocorr K, Jiang Z, Zhuang J, Yuan W, Wu X.

Curr Mol Med. 2018 Mar 9;17(7):509-517. doi: 10.2174/1566524018666180212145714.

7.

Reduced Cardiac Calcineurin Expression Mimics Long-Term Hypoxia-Induced Heart Defects in Drosophila.

Zarndt R, Walls SM, Ocorr K, Bodmer R.

Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001706. doi: 10.1161/CIRCGENETICS.117.001706. Erratum in: Circ Cardiovasc Genet. 2017 Dec;10(6):e000041.

8.

TRiC/CCT chaperonins are essential for maintaining myofibril organization, cardiac physiological rhythm, and lifespan.

Melkani GC, Bhide S, Han A, Vyas J, Livelo C, Bodmer R, Bernstein SI.

FEBS Lett. 2017 Nov;591(21):3447-3458. doi: 10.1002/1873-3468.12860. Epub 2017 Oct 10.

9.

High Fat Diet Feeding and High Throughput Triacylglyceride Assay in Drosophila Melanogaster.

Diop SB, Birse RT, Bodmer R.

J Vis Exp. 2017 Sep 13;(127). doi: 10.3791/56029.

10.

Transcriptomic analysis identifies a role of PI3K-Akt signalling in the responses of skeletal muscle to acute hypoxia in vivo.

Gan Z, Powell FL, Zambon AC, Buchholz KS, Fu Z, Ocorr K, Bodmer R, Moya EA, Stowe JC, Haddad GG, McCulloch AD.

J Physiol. 2017 Sep 1;595(17):5797-5813. doi: 10.1113/JP274556. Epub 2017 Jul 27.

11.

SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila.

Zanon A, Kalvakuri S, Rakovic A, Foco L, Guida M, Schwienbacher C, Serafin A, Rudolph F, Trilck M, Grünewald A, Stanslowsky N, Wegner F, Giorgio V, Lavdas AA, Bodmer R, Pramstaller PP, Klein C, Hicks AA, Pichler I, Seibler P.

Hum Mol Genet. 2017 Jul 1;26(13):2412-2425. doi: 10.1093/hmg/ddx132.

12.

Modest overexpression of FOXO maintains cardiac proteostasis and ameliorates age-associated functional decline.

Blice-Baum AC, Zambon AC, Kaushik G, Viswanathan MC, Engler AJ, Bodmer R, Cammarato A.

Aging Cell. 2017 Feb;16(1):93-103. doi: 10.1111/acel.12543.

13.

Expression patterns of cardiac aging in Drosophila.

Cannon L, Zambon AC, Cammarato A, Zhang Z, Vogler G, Munoz M, Taylor E, Cartry J, Bernstein SI, Melov S, Bodmer R.

Aging Cell. 2017 Feb;16(1):82-92. doi: 10.1111/acel.12559.

14.

Extracellular matrix downregulation in the Drosophila heart preserves contractile function and improves lifespan.

Sessions AO, Kaushik G, Parker S, Raedschelders K, Bodmer R, Van Eyk JE, Engler AJ.

Matrix Biol. 2017 Oct;62:15-27. doi: 10.1016/j.matbio.2016.10.008. Epub 2016 Oct 25.

15.

52 Genetic Loci Influencing Myocardial Mass.

van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano MT, Wang X, Mateo Leach I, Eijgelsheim M, Sotoodehnia N, Hayward C, Sorice R, Meirelles O, Lyytikäinen LP, Polašek O, Tanaka T, Arking DE, Ulivi S, Trompet S, Müller-Nurasyid M, Smith AV, Dörr M, Kerr KF, Magnani JW, Del Greco M F, Zhang W, Nolte IM, Silva CT, Padmanabhan S, Tragante V, Esko T, Abecasis GR, Adriaens ME, Andersen K, Barnett P, Bis JC, Bodmer R, Buckley BM, Campbell H, Cannon MV, Chakravarti A, Chen LY, Delitala A, Devereux RB, Doevendans PA, Dominiczak AF, Ferrucci L, Ford I, Gieger C, Harris TB, Haugen E, Heinig M, Hernandez DG, Hillege HL, Hirschhorn JN, Hofman A, Hubner N, Hwang SJ, Iorio A, Kähönen M, Kellis M, Kolcic I, Kooner IK, Kooner JS, Kors JA, Lakatta EG, Lage K, Launer LJ, Levy D, Lundby A, Macfarlane PW, May D, Meitinger T, Metspalu A, Nappo S, Naitza S, Neph S, Nord AS, Nutile T, Okin PM, Olsen JV, Oostra BA, Penninger JM, Pennacchio LA, Pers TH, Perz S, Peters A, Pinto YM, Pfeufer A, Pilia MG, Pramstaller PP, Prins BP, Raitakari OT, Raychaudhuri S, Rice KM, Rossin EJ, Rotter JI, Schafer S, Schlessinger D, Schmidt CO, Sehmi J, Silljé HHW, Sinagra G, Sinner MF, Slowikowski K, Soliman EZ, Spector TD, Spiering W, Stamatoyannopoulos JA, Stolk RP, Strauch K, Tan ST, Tarasov KV, Trinh B, Uitterlinden AG, van den Boogaard M, van Duijn CM, van Gilst WH, Viikari JS, Visscher PM, Vitart V, Völker U, Waldenberger M, Weichenberger CX, Westra HJ, Wijmenga C, Wolffenbuttel BH, Yang J, Bezzina CR, Munroe PB, Snieder H, Wright AF, Rudan I, Boyer LA, Asselbergs FW, van Veldhuisen DJ, Stricker BH, Psaty BM, Ciullo M, Sanna S, Lehtimäki T, Wilson JF, Bandinelli S, Alonso A, Gasparini P, Jukema JW, Kääb S, Gudnason V, Felix SB, Heckbert SR, de Boer RA, Newton-Cheh C, Hicks AA, Chambers JC, Jamshidi Y, Visel A, Christoffels VM, Isaacs A, Samani NJ, de Bakker PIW.

J Am Coll Cardiol. 2016 Sep 27;68(13):1435-1448. doi: 10.1016/j.jacc.2016.07.729.

16.

A Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in Drosophila.

Achal M, Trujillo AS, Melkani GC, Farman GP, Ocorr K, Viswanathan MC, Kaushik G, Newhard CS, Glasheen BM, Melkani A, Suggs JA, Moore JR, Swank DM, Bodmer R, Cammarato A, Bernstein SI.

J Mol Biol. 2016 Jun 5;428(11):2446-2461. doi: 10.1016/j.jmb.2016.04.021. Epub 2016 Apr 20.

17.

The canonical Wingless signaling pathway is required but not sufficient for inflow tract formation in the Drosophila melanogaster heart.

Trujillo GV, Nodal DH, Lovato CV, Hendren JD, Helander LA, Lovato TL, Bodmer R, Cripps RM.

Dev Biol. 2016 May 1;413(1):16-25. doi: 10.1016/j.ydbio.2016.03.013. Epub 2016 Mar 13.

18.

High throughput physiological screening of iPSC-derived cardiomyocytes for drug development.

Del Álamo JC, Lemons D, Serrano R, Savchenko A, Cerignoli F, Bodmer R, Mercola M.

Biochim Biophys Acta. 2016 Jul;1863(7 Pt B):1717-27. doi: 10.1016/j.bbamcr.2016.03.003. Epub 2016 Mar 4. Review.

19.

SPARC-Dependent Cardiomyopathy in Drosophila.

Hartley PS, Motamedchaboki K, Bodmer R, Ocorr K.

Circ Cardiovasc Genet. 2016 Apr;9(2):119-29. doi: 10.1161/CIRCGENETICS.115.001254. Epub 2016 Feb 2.

20.

Gaining Insights into Diabetic Cardiomyopathy from Drosophila.

Diop SB, Bodmer R.

Trends Endocrinol Metab. 2015 Nov;26(11):618-627. doi: 10.1016/j.tem.2015.09.009. Epub 2015 Oct 16. Review.

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