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Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial.

Heerspink HJL, Parving HH, Andress DL, Bakris G, Correa-Rotter R, Hou FF, Kitzman DW, Kohan D, Makino H, McMurray JJV, Melnick JZ, Miller MG, Pergola PE, Perkovic V, Tobe S, Yi T, Wigderson M, de Zeeuw D; SONAR Committees and Investigators.

Lancet. 2019 Apr 12. pii: S0140-6736(19)30772-X. doi: 10.1016/S0140-6736(19)30772-X. [Epub ahead of print]


Bile acid mediated changes after bariatric surgery: what can we learn from mouse models?

McGlone ER, Tan T, Bloom SR, Walters JRF.

Gastroenterology. 2019 Mar 28. pii: S0016-5085(19)34633-5. doi: 10.1053/j.gastro.2019.02.048. [Epub ahead of print] No abstract available.


Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol.

Ray KK, Bays HE, Catapano AL, Lalwani ND, Bloedon LT, Sterling LR, Robinson PL, Ballantyne CM; CLEAR Harmony Trial.

N Engl J Med. 2019 Mar 14;380(11):1022-1032. doi: 10.1056/NEJMoa1803917.


A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes.

Yuen LH, Dana S, Liu Y, Bloom SI, Thorsell AG, Neri D, Donato AJ, Kireev D, Schüler H, Franzini RM.

J Am Chem Soc. 2019 Apr 3;141(13):5169-5181. doi: 10.1021/jacs.8b08039. Epub 2019 Mar 19.


Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study.

Kennedy NA, Heap GA, Green HD, Hamilton B, Bewshea C, Walker GJ, Thomas A, Nice R, Perry MH, Bouri S, Chanchlani N, Heerasing NM, Hendy P, Lin S, Gaya DR, Cummings JRF, Selinger CP, Lees CW, Hart AL, Parkes M, Sebastian S, Mansfield JC, Irving PM, Lindsay J, Russell RK, McDonald TJ, McGovern D, Goodhand JR, Ahmad T; UK Inflammatory Bowel Disease Pharmacogenetics Study Group.

Lancet Gastroenterol Hepatol. 2019 May;4(5):341-353. doi: 10.1016/S2468-1253(19)30012-3. Epub 2019 Feb 27.


Current Practices in Ileal Pouch Surveillance for Patients with Ulcerative Colitis: A Multinational, Retrospective Cohort Study.

Samaan MA, Forsyth K, Segal JP, de Jong D, Vleugels J, Elkady S, Kabir M, Campbell S, Kok K, Armstrong DG, Penez L, Arenaza AP, Seward E, Vega R, Mehta S, Rahman F, McCartney S, Bloom S, Patel K, Pollok R, Westcott E, Darakhshan A, Williams A, Koumoutsos I, Ray S, Mawdsley J, Anderson S, Sanderson JD, Dekker E, D'Haens GR, Hart A, Irving PM.

J Crohns Colitis. 2018 Dec 24. doi: 10.1093/ecco-jcc/jjy225. [Epub ahead of print]


Funding and services needed to achieve universal health coverage: applications of global, regional, and national estimates of utilisation of outpatient visits and inpatient admissions from 1990 to 2016, and unit costs from 1995 to 2016.

Moses MW, Pedroza P, Baral R, Bloom S, Brown J, Chapin A, Compton K, Eldrenkamp E, Fullman N, Mumford JE, Nandakumar V, Rosettie K, Sadat N, Shonka T, Flaxman A, Vos T, Murray CJL, Weaver MR.

Lancet Public Health. 2019 Jan;4(1):e49-e73. doi: 10.1016/S2468-2667(18)30213-5. Epub 2018 Dec 12.


Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial.

FOCUS Trial Collaboration.

Lancet. 2019 Jan 19;393(10168):265-274. doi: 10.1016/S0140-6736(18)32823-X. Epub 2018 Dec 5.


Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress.

Morgan RG, Walker AE, Trott DW, Machin DR, Henson GD, Reihl KD, Cawthon RM, Denchi EL, Liu Y, Bloom SI, Phuong TT, Richardson RS, Lesniewski LA, Donato AJ.

J Mol Cell Cardiol. 2019 Feb;127:74-82. doi: 10.1016/j.yjmcc.2018.11.014. Epub 2018 Nov 29.


Bile acids and the metabolic syndrome.

McGlone ER, Bloom SR.

Ann Clin Biochem. 2019 Mar 4:4563218817798. doi: 10.1177/0004563218817798. [Epub ahead of print]


L-Arginine Increases Postprandial Circulating GLP-1 and PYY Levels in Humans.

Amin A, Neophytou C, Thein S, Martin NM, Alamshah A, Spreckley E, Bloom SR, Murphy KG.

Obesity (Silver Spring). 2018 Nov;26(11):1721-1726. doi: 10.1002/oby.22323.


Modulations of human resting brain connectivity by kisspeptin enhance sexual and emotional functions.

Comninos AN, Demetriou L, Wall MB, Shah AJ, Clarke SA, Narayanaswamy S, Nesbitt A, Izzi-Engbeaya C, Prague JK, Abbara A, Ratnasabapathy R, Yang L, Salem V, Nijher GM, Jayasena CN, Tanner M, Bassett P, Mehta A, McGonigle J, Rabiner EA, Bloom SR, Dhillo WS.

JCI Insight. 2018 Oct 18;3(20). pii: 121958. doi: 10.1172/jci.insight.121958.


Implications of endothelial shear stress on systemic sclerosis vasculopathy and treatment.

Frech TM, Machin DR, Murtaugh MA, Stoddard GJ, Bloom SI, Phibbs JV, Donato AJ.

Clin Exp Rheumatol. 2018 Jul-Aug;36 Suppl 113(4):175-182. Epub 2018 Sep 20. Review.


Implementation of interventions informed by precursor functional analyses with young children: A replication.

Hoffmann AN, Sellers TP, Halversen H, Bloom SE.

J Appl Behav Anal. 2018 Oct;51(4):879-889. doi: 10.1002/jaba.502. Epub 2018 Sep 11.


A New Look at Familial Risk of Inflammatory Bowel Disease in the Ashkenazi Jewish Population.

Schiff ER, Frampton M, Semplici F, Bloom SL, McCartney SA, Vega R, Lovat LB, Wood E, Hart AL, Crespi D, Furman MA, Mann S, Murray CD, Segal AW, Levine AP.

Dig Dis Sci. 2018 Nov;63(11):3049-3057. doi: 10.1007/s10620-018-5219-9. Epub 2018 Sep 3.


Reply: Critical Care Pharmacists and Medication Management in an ICU Recovery Center.

Stollings JL, Bloom SL, Sevin CM.

Ann Pharmacother. 2019 Jan;53(1):106. doi: 10.1177/1060028018799501. Epub 2018 Sep 1. No abstract available.


Rare coding variant analysis in a large cohort of Ashkenazi Jewish families with inflammatory bowel disease.

Schiff ER, Frampton M, Ben-Yosef N, Avila BE, Semplici F, Pontikos N, Bloom SL, McCartney SA, Vega R, Lovat LB, Wood E, Hart A, Israeli E, Crespi D, Furman MA, Mann S, Murray CD, Segal AW, Levine AP.

Hum Genet. 2018 Sep;137(9):723-734. doi: 10.1007/s00439-018-1927-7. Epub 2018 Aug 22.


No Guts, No Loss: Toward the Ideal Treatment for Obesity in the Twenty-First Century.

Hope DCD, Tan TMM, Bloom SR.

Front Endocrinol (Lausanne). 2018 Aug 15;9:442. doi: 10.3389/fendo.2018.00442. eCollection 2018. Review.


Magnetic resonance enterography, small bowel ultrasound and colonoscopy to diagnose and stage Crohn's disease: patient acceptability and perceived burden.

Miles A, Bhatnagar G, Halligan S, Gupta A, Tolan D, Zealley I, Taylor SA; METRIC investigators.

Eur Radiol. 2019 Mar;29(3):1083-1093. doi: 10.1007/s00330-018-5661-2. Epub 2018 Aug 20.


Double-Blind Phase III Trial of Adjuvant Chemotherapy With and Without Bevacizumab in Patients With Lymph Node-Positive and High-Risk Lymph Node-Negative Breast Cancer (E5103).

Miller KD, O'Neill A, Gradishar W, Hobday TJ, Goldstein LJ, Mayer IA, Bloom S, Brufsky AM, Tevaarwerk AJ, Sparano JA, Le-Lindqwister NA, Hendricks CB, Northfelt DW, Dang CT, Sledge GW Jr.

J Clin Oncol. 2018 Sep 1;36(25):2621-2629. doi: 10.1200/JCO.2018.79.2028. Epub 2018 Jul 24.


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