Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 55

1.

Bloodstream Stability Predetermines the Antitumor Efficacy of Micellar Polymer-Doxorubicin Drug Conjugates with pH-Triggered Drug Release.

Chytil P, Šírová M, Kudláčová J, Říhová B, Ulbrich K, Etrych T.

Mol Pharm. 2018 Sep 4;15(9):3654-3663. doi: 10.1021/acs.molpharmaceut.8b00156. Epub 2018 Mar 21.

PMID:
29543465
2.

Polymer donors of nitric oxide improve the treatment of experimental solid tumours with nanosized polymer therapeutics.

Šírová M, Horková V, Etrych T, Chytil P, Říhová B, Studenovský M.

J Drug Target. 2017 Nov - Dec;25(9-10):796-808. doi: 10.1080/1061186X.2017.1358724. Epub 2017 Aug 7.

PMID:
28726521
3.

The structure of polymer carriers controls the efficacy of the experimental combination treatment of tumors with HPMA copolymer conjugates carrying doxorubicin and docetaxel.

Šírová M, Strohalm J, Chytil P, Lidický O, Tomala J, Říhová B, Etrych T.

J Control Release. 2017 Jan 28;246:1-11. doi: 10.1016/j.jconrel.2016.12.004. Epub 2016 Dec 6.

PMID:
27940304
4.

Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate.

Sivak L, Subr V, Tomala J, Rihova B, Strohalm J, Etrych T, Kovar M.

Biomaterials. 2017 Jan;115:65-80. doi: 10.1016/j.biomaterials.2016.11.013. Epub 2016 Nov 12.

PMID:
27886555
5.

Polymer inhibitors of ABC transporter overcoming multidrug resistance: Synthesis, characterization and in vitro evaluation.

Šubr V, Koziolová E, Sivák L, Říhová B, Kovář M, Ulbrich K.

J Control Release. 2015 Sep 10;213:e107-8. doi: 10.1016/j.jconrel.2015.05.180. Epub 2015 Aug 19. No abstract available.

PMID:
27005035
6.

The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia.

Tomalova B, Sirova M, Rossmann P, Pola R, Strohalm J, Chytil P, Cerny V, Tomala J, Kabesova M, Rihova B, Ulbrich K, Etrych T, Kovar M.

J Control Release. 2016 Feb 10;223:1-10. doi: 10.1016/j.jconrel.2015.12.023. Epub 2015 Dec 18.

PMID:
26708020
7.

Novel IL-2-Poly(HPMA)Nanoconjugate Based Immunotherapy.

Votavova P, Tomala J, Subr V, Strohalm J, Ulbrich K, Rihova B, Kovar M.

J Biomed Nanotechnol. 2015 Sep;11(9):1662-73.

PMID:
26485935
8.

Cancer-associated fibroblasts are not formed from cancer cells by epithelial-to-mesenchymal transition in nu/nu mice.

Dvořánková B, Smetana K Jr, Říhová B, Kučera J, Mateu R, Szabo P.

Histochem Cell Biol. 2015 May;143(5):463-9. doi: 10.1007/s00418-014-1293-z. Epub 2014 Nov 12.

PMID:
25387587
9.

Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours.

Etrych T, Subr V, Laga R, Ríhová B, Ulbrich K.

Eur J Pharm Sci. 2014 Jul 16;58:1-12. doi: 10.1016/j.ejps.2014.02.016. Epub 2014 Mar 13.

PMID:
24632485
10.

HPMA copolymer conjugates of DOX and mitomycin C for combination therapy: physicochemical characterization, cytotoxic effects, combination index analysis, and anti-tumor efficacy.

Kostková H, Etrych T, Ríhová B, Kostka L, Starovoytová L, Kovář M, Ulbrich K.

Macromol Biosci. 2013 Dec;13(12):1648-60. doi: 10.1002/mabi.201300288. Epub 2013 Sep 12.

PMID:
24031022
11.

Immunocompatibility evaluation of hydrogel-coated polyimide implants for applications in regenerative medicine.

Sirova M, Van Vlierberghe S, Matyasova V, Rossmann P, Schacht E, Dubruel P, Rihova B.

J Biomed Mater Res A. 2014 Jun;102(6):1982-90. doi: 10.1002/jbm.a.34873. Epub 2013 Jul 30.

PMID:
23852806
12.

Fine needle aspiration biopsy proves increased T-lymphocyte proliferation in tumor and decreased metastatic infiltration after treatment with doxorubicin bound to PHPMA copolymer carrier.

Betka J, Hovorka O, Boucek J, Ulbrich K, Etrych T, Rihova B.

J Drug Target. 2013 Aug;21(7):648-61. doi: 10.3109/1061186X.2013.792345. Epub 2013 Apr 26.

PMID:
23621109
13.

Chimera of IL-2 linked to light chain of anti-IL-2 mAb mimics IL-2/anti-IL-2 mAb complexes both structurally and functionally.

Tomala J, Kovarova J, Kabesova M, Votavova P, Chmelova H, Dvorakova B, Rihova B, Kovar M.

ACS Chem Biol. 2013 May 17;8(5):871-6. doi: 10.1021/cb3007242. Epub 2013 Mar 5.

PMID:
23419043
14.

Combination chemotherapy using core-shell nanoparticles through the self-assembly of HPMA-based copolymers and degradable polyester.

Jäger E, Jäger A, Chytil P, Etrych T, Ríhová B, Giacomelli FC, Stěpánek P, Ulbrich K.

J Control Release. 2013 Jan 28;165(2):153-61. doi: 10.1016/j.jconrel.2012.11.009. Epub 2012 Nov 23.

PMID:
23178950
15.

Polymer carriers for anticancer drugs targeted to EGF receptor.

Studenovsky M, Pola R, Pechar M, Etrych T, Ulbrich K, Kovar L, Kabesova M, Rihova B.

Macromol Biosci. 2012 Dec;12(12):1714-20. doi: 10.1002/mabi.201200270. Epub 2012 Oct 17.

PMID:
23077133
16.

Dimerization of an immunoactivating peptide derived from mycobacterial hsp65 using N-hydroxysuccinimide based bifunctional reagents is critical for its antitumor properties.

Bezouška K, Kubínková Z, Stříbný J, Volfová B, Pompach P, Kuzma M, Šírová M, Říhová B.

Bioconjug Chem. 2012 Oct 17;23(10):2032-41. doi: 10.1021/bc300056x. Epub 2012 Sep 28. Retraction in: Bioconjug Chem. 2014 Feb 19;25(2):451.

PMID:
22988810
17.

Czech Immunological Society (CIS): Immunological "enthusiasm" that began in the 1950s and 60s.

Rihova B.

Eur J Immunol. 2012 Jul;42(7):1658-61. doi: 10.1002/eji.2012700045. No abstract available.

18.

HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity.

Etrych T, Subr V, Strohalm J, Sírová M, Ríhová B, Ulbrich K.

J Control Release. 2012 Dec 28;164(3):346-54. doi: 10.1016/j.jconrel.2012.06.029. Epub 2012 Jun 30.

PMID:
22759979
19.

Synergistic effect of EMF-BEMER-type pulsed weak electromagnetic field and HPMA-bound doxorubicin on mouse EL4 T-cell lymphoma.

Říhová B, Etrych T, Šírová M, Tomala J, Ulbrich K, Kovář M.

J Drug Target. 2011 Dec;19(10):890-9. doi: 10.3109/1061186X.2011.622403. Epub 2011 Oct 10.

PMID:
21981636
20.

Biodegradable star HPMA polymer-drug conjugates: Biodegradability, distribution and anti-tumor efficacy.

Etrych T, Kovář L, Strohalm J, Chytil P, Ríhová B, Ulbrich K.

J Control Release. 2011 Sep 25;154(3):241-8. doi: 10.1016/j.jconrel.2011.06.015. Epub 2011 Jun 15.

PMID:
21699933

Supplemental Content

Loading ...
Support Center