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Antimicrob Agents Chemother. 2000 Oct;44(10):2903-4.

Bioavailability of praziquantel increases with concomitant administration of food.

Author information

1
Instituto Nacional de Neurologia y Neurocirugia, Mexico City, Mexico.

Abstract

In the present study we found that after a single oral dose of 1,800 mg of praziquantel, following a high-lipid diet and a high-carbohydrate diet, the maximum levels in plasma increased 243 and 515% and the area under the plasma concentration curve from 0 to 8 h increased 180 and 271%, respectively.

PMID:
10991886
PMCID:
PMC90177
DOI:
10.1128/aac.44.10.2903-2904.2000
[Indexed for MEDLINE]
Free PMC Article

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