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Page 1
Emerging Role of Nuclear Receptors for the Treatment of NAFLD and NASH.
Welch RD, Billon C, Losby M, Bedia-Diaz G, Fang Y, Avdagic A, Elgendy B, Burris TP, Griffett K. Welch RD, et al. Among authors: bedia diaz g. Metabolites. 2022 Mar 11;12(3):238. doi: 10.3390/metabo12030238. Metabolites. 2022. PMID: 35323681 Free PMC article. Review.
Antihyperlipidemic Activity of Gut-Restricted LXR Inverse Agonists.
Griffett K, Hayes M, Bedia-Diaz G, Appourchaux K, Sanders R, Boeckman MP, Koelblen T, Zhang J, Schulman IG, Elgendy B, Burris TP. Griffett K, et al. Among authors: bedia diaz g. ACS Chem Biol. 2022 May 20;17(5):1143-1154. doi: 10.1021/acschembio.2c00057. Epub 2022 Apr 13. ACS Chem Biol. 2022. PMID: 35417135
REV-ERB agonism improves liver pathology in a mouse model of NASH.
Griffett K, Bedia-Diaz G, Elgendy B, Burris TP. Griffett K, et al. Among authors: bedia diaz g. PLoS One. 2020 Oct 1;15(10):e0236000. doi: 10.1371/journal.pone.0236000. eCollection 2020. PLoS One. 2020. PMID: 33002003 Free PMC article.
Doubled lifespan and patient-like pathologies in progeria mice fed high-fat diet.
Kreienkamp R, Billon C, Bedia-Diaz G, Albert CJ, Toth Z, Butler AA, McBride-Gagyi S, Ford DA, Baldan A, Burris TP, Gonzalo S. Kreienkamp R, et al. Among authors: bedia diaz g. Aging Cell. 2019 Feb;18(1):e12852. doi: 10.1111/acel.12852. Epub 2018 Dec 12. Aging Cell. 2019. PMID: 30548460 Free PMC article.
The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids.
Griffett K, Bedia-Diaz G, Hegazy L, de Vera IMS, Wanninayake US, Billon C, Koelblen T, Wilhelm ML, Burris TP. Griffett K, et al. Among authors: bedia diaz g. Cell Chem Biol. 2020 Oct 15;27(10):1272-1284.e4. doi: 10.1016/j.chembiol.2020.07.013. Epub 2020 Aug 6. Cell Chem Biol. 2020. PMID: 32763139 Free article.