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Items: 1 to 20 of 141


Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury.

Lau A, Chung H, Komada T, Platnich JM, Sandall CF, Choudhury SR, Chun J, Naumenko V, Surewaard BG, Nelson MC, Ulke-Lemée A, Beck PL, Benediktsson H, Jevnikar AM, Snelgrove SL, Hickey MJ, Senger DL, James MT, Macdonald JA, Kubes P, Jenne CN, Muruve DA.

J Clin Invest. 2018 Jun 4. pii: 96640. doi: 10.1172/JCI96640. [Epub ahead of print]


Iron Sequestration in Microbiota Biofilms As A Novel Strategy for Treating Inflammatory Bowel Disease.

Motta JP, Allain T, Green-Harrison LE, Groves RA, Feener T, Ramay H, Beck PL, Lewis IA, Wallace JL, Buret AG.

Inflamm Bowel Dis. 2018 Jun 8;24(7):1493-1502. doi: 10.1093/ibd/izy116.


Neutralization of IL-15 abrogates experimental immune-mediated cholangitis in diet-induced obese mice.

Reyes JL, Vannan DT, Vo T, Gulamhusein A, Beck PL, Reimer RA, Eksteen B.

Sci Rep. 2018 Feb 15;8(1):3127. doi: 10.1038/s41598-018-21112-7.


Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD.

Komada T, Chung H, Lau A, Platnich JM, Beck PL, Benediktsson H, Duff HJ, Jenne CN, Muruve DA.

J Am Soc Nephrol. 2018 Apr;29(4):1165-1181. doi: 10.1681/ASN.2017080863. Epub 2018 Feb 9.


Not Your Ordinary Ulcer: A Cautionary Tale of an Uncommon Condition.

Nguyen HH, Beck PL.

Gastroenterology. 2017 Dec;153(6):1484-1485. doi: 10.1053/j.gastro.2017.04.013. Epub 2017 Nov 2. No abstract available.


Tumor necrosis factor α decreases aquaporin 3 expression in intestinal epithelial cells through inhibition of constitutive transcription.

Peplowski MA, Vegso AJ, Iablokov V, Dicay M, Zaheer RS, Renaux B, Proud D, Hollenberg MD, Beck PL, MacNaughton WK.

Physiol Rep. 2017 Oct;5(19). pii: e13451. doi: 10.14814/phy2.13451. Epub 2017 Oct 16.


The NOD2-Smoking Interaction in Crohn's Disease is likely Specific to the 1007fs Mutation and may be Explained by Age at Diagnosis: A Meta-Analysis and Case-Only Study.

Kuenzig ME, Yim J, Coward S, Eksteen B, Seow CH, Barnabe C, Barkema HW, Silverberg MS, Lakatos PL, Beck PL, Fedorak R, Dieleman LA, Madsen K, Panaccione R, Ghosh S, Kaplan GG.

EBioMedicine. 2017 Jul;21:188-196. doi: 10.1016/j.ebiom.2017.06.012. Epub 2017 Jun 16. Review.


Microscopic Colitis Evolved Into Inflammatory Bowel Diseases Is Characterized by Increased Th1/Tc1 Cells in Colonic Mucosal Lamina Propria.

Li J, Yan Y, Meng Z, Liu S, Beck PL, Ghosh S, Qian J, Gui X.

Dig Dis Sci. 2017 Oct;62(10):2755-2767. doi: 10.1007/s10620-017-4636-5. Epub 2017 Jun 9.


Crossover Subsets of CD4+ T Lymphocytes in the Intestinal Lamina Propria of Patients with Crohn's Disease and Ulcerative Colitis.

Li J, Ueno A, Iacucci M, Fort Gasia M, Jijon HB, Panaccione R, Kaplan GG, Beck PL, Luider J, Barkema HW, Qian J, Gui X, Ghosh S.

Dig Dis Sci. 2017 Sep;62(9):2357-2368. doi: 10.1007/s10620-017-4596-9. Epub 2017 Jun 1.


Career and research outcomes of the physician-scientist training program at the University of Calgary: a retrospective cohort study.

Bau JT, Frolkis AD, Nathoo N, Yipp BG, Hollenberg MD, Beck PL.

CMAJ Open. 2017 May 15;5(2):E395-E401. doi: 10.9778/cmajo.20160103. Epub 2017 May 15.


The effects of pregnancy on the pharmacokinetics of infliximab and adalimumab in inflammatory bowel disease.

Seow CH, Leung Y, Vande Casteele N, Ehteshami Afshar E, Tanyingoh D, Bindra G, Stewart MJ, Beck PL, Kaplan GG, Ghosh S, Panaccione R.

Aliment Pharmacol Ther. 2017 May;45(10):1329-1338. doi: 10.1111/apt.14040. Epub 2017 Mar 20.


Giardia duodenalis induces pathogenic dysbiosis of human intestinal microbiota biofilms.

Beatty JK, Akierman SV, Motta JP, Muise S, Workentine ML, Harrison JJ, Bhargava A, Beck PL, Rioux KP, McKnight GW, Wallace JL, Buret AG.

Int J Parasitol. 2017 May;47(6):311-326. doi: 10.1016/j.ijpara.2016.11.010. Epub 2017 Feb 22.


Exaggerated IL-15 and Altered Expression of foxp3+ Cell-Derived Cytokines Contribute to Enhanced Colitis in Nlrp3-/- Mice.

Hirota SA, Ueno A, Tulk SE, Becker HM, Schenck LP, Potentier MS, Li Y, Ghosh S, Muruve DA, MacDonald JA, Beck PL.

Mediators Inflamm. 2016;2016:5637685. doi: 10.1155/2016/5637685. Epub 2016 Aug 17.


Novel CD8+ T-Cell Subsets Demonstrating Plasticity in Patients with Inflammatory Bowel Disease.

Tom MR, Li J, Ueno A, Fort Gasia M, Chan R, Hung DY, Chenoo S, Iacucci M, Jijon HB, Kaplan GG, Beck PL, Panaccione R, Barkema HW, Buret AG, Yajnik V, Ghosh S.

Inflamm Bowel Dis. 2016 Jul;22(7):1596-608. doi: 10.1097/MIB.0000000000000848.


Profiles of Lamina Propria T Helper Cell Subsets Discriminate Between Ulcerative Colitis and Crohn's Disease.

Li J, Ueno A, Fort Gasia M, Luider J, Wang T, Hirota C, Jijon HB, Deane M, Tom M, Chan R, Barkema HW, Beck PL, Kaplan GG, Panaccione R, Qian J, Iacucci M, Gui X, Ghosh S.

Inflamm Bowel Dis. 2016 Aug;22(8):1779-92. doi: 10.1097/MIB.0000000000000811.


Ulcerative Colitis Patients With Clostridium difficile are at Increased Risk of Death, Colectomy, and Postoperative Complications: A Population-Based Inception Cohort Study.

Negrón ME, Rezaie A, Barkema HW, Rioux K, De Buck J, Checkley S, Beck PL, Carroll M, Fedorak RN, Dieleman L, Panaccione R, Ghosh S, Kaplan GG.

Am J Gastroenterol. 2016 May;111(5):691-704. doi: 10.1038/ajg.2016.106. Epub 2016 Apr 19.


Unique microbial-derived volatile organic compounds in portal venous circulation in murine non-alcoholic fatty liver disease.

Reid DT, McDonald B, Khalid T, Vo T, Schenck LP, Surette MG, Beck PL, Reimer RA, Probert CS, Rioux KP, Eksteen B.

Biochim Biophys Acta. 2016 Jul;1862(7):1337-44. doi: 10.1016/j.bbadis.2016.04.005. Epub 2016 Apr 13.


Lost: Young Canadian physician-scientists need a map.

Lewinson RT, Keough MB, Beck PL, Hollenberg MD, Yipp BG.

Sci Transl Med. 2016 Mar 9;8(329):329fs6. doi: 10.1126/scitranslmed.aad4355. Review.


NLRP3 regulates a non-canonical platform for caspase-8 activation during epithelial cell apoptosis.

Chung H, Vilaysane A, Lau A, Stahl M, Morampudi V, Bondzi-Simpson A, Platnich JM, Bracey NA, French MC, Beck PL, Chun J, Vallance BA, Muruve DA.

Cell Death Differ. 2016 Aug;23(8):1331-46. doi: 10.1038/cdd.2016.14. Epub 2016 Feb 19.


Proceedings from the 6th Annual University of Calgary Leaders in Medicine Research Symposium.

Roberts JI, Beatty JK, Peplowski MA, Keough MB, Yipp BG, Hollenberg MD, Beck PL.

Clin Invest Med. 2015 Dec 4;38(6):E318-50.


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