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Items: 1 to 20 of 90

1.

The Activity of Kv 11.1 Potassium Channel Modulates F-Actin Organization During Cell Migration of Pancreatic Ductal Adenocarcinoma Cells.

Manoli S, Coppola S, Duranti C, Lulli M, Magni L, Kuppalu N, Nielsen N, Schmidt T, Schwab A, Becchetti A, Arcangeli A.

Cancers (Basel). 2019 Jan 23;11(2). pii: E135. doi: 10.3390/cancers11020135.

2.

Ion Channel Conformations Regulate Integrin-Dependent Signaling.

Becchetti A, Petroni G, Arcangeli A.

Trends Cell Biol. 2019 Jan 8. pii: S0962-8924(18)30235-6. doi: 10.1016/j.tcb.2018.12.005. [Epub ahead of print] Review.

PMID:
30635161
3.

Postnatal Changes in K+/Cl- Cotransporter-2 Expression in the Forebrain of Mice Bearing a Mutant Nicotinic Subunit Linked to Sleep-Related Epilepsy.

Amadeo A, Coatti A, Aracri P, Ascagni M, Iannantuoni D, Modena D, Carraresi L, Brusco S, Meneghini S, Arcangeli A, Pasini ME, Becchetti A.

Neuroscience. 2018 Aug 21;386:91-107. doi: 10.1016/j.neuroscience.2018.06.030. Epub 2018 Jun 24.

PMID:
29949744
4.

The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells.

Pillozzi S, D'Amico M, Bartoli G, Gasparoli L, Petroni G, Crociani O, Marzo T, Guerriero A, Messori L, Severi M, Udisti R, Wulff H, Chandy KG, Becchetti A, Arcangeli A.

Br J Cancer. 2018 Jan;118(2):200-212. doi: 10.1038/bjc.2017.392. Epub 2017 Nov 21.

5.

Mesoporous silica nanoparticles trigger mitophagy in endothelial cells and perturb neuronal network activity in a size- and time-dependent manner.

Orlando A, Cazzaniga E, Tringali M, Gullo F, Becchetti A, Minniti S, Taraballi F, Tasciotti E, Re F.

Int J Nanomedicine. 2017 May 8;12:3547-3559. doi: 10.2147/IJN.S127663. eCollection 2017.

6.

The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression.

Becchetti A, Crescioli S, Zanieri F, Petroni G, Mercatelli R, Coppola S, Gasparoli L, D'Amico M, Pillozzi S, Crociani O, Stefanini M, Fiore A, Carraresi L, Morello V, Manoli S, Brizzi MF, Ricci D, Rinaldi M, Masi A, Schmidt T, Quercioli F, Defilippi P, Arcangeli A.

Sci Signal. 2017 Apr 4;10(473). pii: eaaf3236. doi: 10.1126/scisignal.aaf3236.

PMID:
28377405
7.

hERG Channels: From Antitargets to Novel Targets for Cancer Therapy.

Arcangeli A, Becchetti A.

Clin Cancer Res. 2017 Jan 1;23(1):3-5. doi: 10.1158/1078-0432.CCR-16-2322. Epub 2016 Nov 30.

8.

α4β2 nicotinic receptors stimulate GABA release onto fast-spiking cells in layer V of mouse prefrontal (Fr2) cortex.

Aracri P, Meneghini S, Coatti A, Amadeo A, Becchetti A.

Neuroscience. 2017 Jan 6;340:48-61. doi: 10.1016/j.neuroscience.2016.10.045. Epub 2016 Oct 26.

9.

Neuron-glia cross talk revealed in reverberating networks by simultaneous extracellular recording of spikes and astrocytes' glutamate transporter and K+ currents.

Wanke E, Gullo F, Dossi E, Valenza G, Becchetti A.

J Neurophysiol. 2016 Dec 1;116(6):2706-2719. doi: 10.1152/jn.00509.2016. Epub 2016 Sep 28.

10.

Macrolide antibiotics exert antileukemic effects by modulating the autophagic flux through inhibition of hERG1 potassium channels.

Pillozzi S, Masselli M, Gasparoli L, D'Amico M, Polletta L, Veltroni M, Favre C, Basso G, Becchetti A, Arcangeli A.

Blood Cancer J. 2016 May 13;6:e423. doi: 10.1038/bcj.2016.32. No abstract available.

11.

Why we forget our dreams: Acetylcholine and norepinephrine in wakefulness and REM sleep.

Becchetti A, Amadeo A.

Behav Brain Sci. 2016 Jan;39:e202. doi: 10.1017/S0140525X15001739.

PMID:
28347366
12.

Agonist and antagonist effects of tobacco-related nitrosamines on human α4β2 nicotinic acetylcholine receptors.

Brusco S, Ambrosi P, Meneghini S, Becchetti A.

Front Pharmacol. 2015 Sep 22;6:201. doi: 10.3389/fphar.2015.00201. eCollection 2015.

13.

Novel perspectives in cancer therapy: Targeting ion channels.

Arcangeli A, Becchetti A.

Drug Resist Updat. 2015 Jul-Aug;21-22:11-9. doi: 10.1016/j.drup.2015.06.002. Epub 2015 Jul 6.

PMID:
26183291
14.

Commentary: "Comparison of spike parameters from optically identified GABAergic and glutamatergic neurons in sparse cortical cultures".

Becchetti A, Wanke E.

Front Cell Neurosci. 2015 Apr 22;9:157. doi: 10.3389/fncel.2015.00157. eCollection 2015. No abstract available.

15.

Nocturnal frontal lobe epilepsy with paroxysmal arousals due to CHRNA2 loss of function.

Conti V, Aracri P, Chiti L, Brusco S, Mari F, Marini C, Albanese M, Marchi A, Liguori C, Placidi F, Romigi A, Becchetti A, Guerrini R.

Neurology. 2015 Apr 14;84(15):1520-8. doi: 10.1212/WNL.0000000000001471. Epub 2015 Mar 13.

16.

The role of nicotinic acetylcholine receptors in autosomal dominant nocturnal frontal lobe epilepsy.

Becchetti A, Aracri P, Meneghini S, Brusco S, Amadeo A.

Front Physiol. 2015 Feb 11;6:22. doi: 10.3389/fphys.2015.00022. eCollection 2015. Review.

17.

New pyrimido-indole compound CD-160130 preferentially inhibits the KV11.1B isoform and produces antileukemic effects without cardiotoxicity.

Gasparoli L, D'Amico M, Masselli M, Pillozzi S, Caves R, Khuwaileh R, Tiedke W, Mugridge K, Pratesi A, Mitcheson JS, Basso G, Becchetti A, Arcangeli A.

Mol Pharmacol. 2015 Feb;87(2):183-96. doi: 10.1124/mol.114.094920. Epub 2014 Nov 19.

PMID:
25411366
18.

Empirically founded genotype-phenotype maps from mammalian cyclic nucleotide-gated ion channels.

Becchetti A.

J Theor Biol. 2014 Dec 21;363:205-15. doi: 10.1016/j.jtbi.2014.08.038. Epub 2014 Aug 27.

PMID:
25172772
19.

Multi-electrode array study of neuronal cultures expressing nicotinic β2-V287L subunits, linked to autosomal dominant nocturnal frontal lobe epilepsy. An in vitro model of spontaneous epilepsy.

Gullo F, Manfredi I, Lecchi M, Casari G, Wanke E, Becchetti A.

Front Neural Circuits. 2014 Jul 24;8:87. doi: 10.3389/fncir.2014.00087. eCollection 2014.

20.

NAMI-A is highly cytotoxic toward leukaemia cell lines: evidence of inhibition of KCa 3.1 channels.

Pillozzi S, Gasparoli L, Stefanini M, Ristori M, D'Amico M, Alessio E, Scaletti F, Becchetti A, Arcangeli A, Messori L.

Dalton Trans. 2014 Aug 28;43(32):12150-5. doi: 10.1039/c4dt01356e.

PMID:
24975719

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