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Serially measured high-sensitivity cardiac troponin T, N-terminal-pro-B-type natriuretic peptide, high-sensitivity C-reactive protein, and growth differentiation factor 15 for risk assessment after acute coronary syndrome: the BIOMArCS cohort.
Gürgöze MT, Akkerhuis KM, Oemrawsingh RM, Umans VAWM, Kietselaer B, Schotborgh CE, Ronner E, Lenderink T, Aksoy I, van der Harst P, Asselbergs FW, Maas AC, Oude Ophuis AJ, Krenning B, de Winter RJ, The SHK, Wardeh AJ, Hermans WRM, Cramer GE, van Gorp I, de Rijke YB, van Schaik RHN, Boersma E. Gürgöze MT, et al. Eur Heart J Acute Cardiovasc Care. 2023 Jul 7;12(7):451-461. doi: 10.1093/ehjacc/zuad042. Eur Heart J Acute Cardiovasc Care. 2023. PMID: 37096818 Free PMC article.
The aim was to explore the prognostic value of four, serially measured biomarkers in a large, real-world cohort of post-ACS patients. METHODS AND RESULTS: BIOMArCS is a prospective, multi-centre, observational study in 844 post-ACS patients in whom 12 218 blood samples (me …
The aim was to explore the prognostic value of four, serially measured biomarkers in a large, real-world cohort of post-ACS patients. METHOD …
Temporal Pattern of Growth Differentiation Factor-15 Protein After Acute Coronary Syndrome (From the BIOMArCS Study).
Buljubasic N, Vroegindewey MM, Oemrawsingh RM, Asselbergs FW, Cramer E, Liem A, van der Harst P, Maas A, Ronner E, Schotborgh C, Wardeh AJ, Akkerhuis KM, Boersma E; BIOMArCS investigators. Buljubasic N, et al. Am J Cardiol. 2019 Jul 1;124(1):8-13. doi: 10.1016/j.amjcard.2019.03.049. Epub 2019 Apr 18. Am J Cardiol. 2019. PMID: 31047655 Free article.
We conducted a nested case-control study within our multicenter, prospective, observational biomarker study (BIOMArCS) of 844 ACS patients. Following an index ACS event, high-frequency blood sampling was performed during 1-year of follow-up. ...
We conducted a nested case-control study within our multicenter, prospective, observational biomarker study (BIOMArCS) of 844 ACS pat …
Cohort profile of BIOMArCS: the BIOMarker study to identify the Acute risk of a Coronary Syndrome-a prospective multicentre biomarker study conducted in the Netherlands.
Oemrawsingh RM, Akkerhuis KM, Umans VA, Kietselaer B, Schotborgh C, Ronner E, Lenderink T, Liem A, Haitsma D, van der Harst P, Asselbergs FW, Maas A, Oude Ophuis AJ, Ilmer B, Dijkgraaf R, de Winter RJ, The SH, Wardeh AJ, Hermans W, Cramer E, van Schaik RH, Hoefer IE, Doevendans PA, Simoons ML, Boersma E. Oemrawsingh RM, et al. BMJ Open. 2016 Dec 23;6(12):e012929. doi: 10.1136/bmjopen-2016-012929. BMJ Open. 2016. PMID: 28011810 Free PMC article.
The BIOMarker study to identify the Acute risk of a Coronary Syndrome (BIOMArCS) was designed to evaluate whether repeated measurements of multiple biomarkers can predict such 'vulnerable periods'. PARTICIPANTS: BIOMArCS is a multicentre, prospective, observational …
The BIOMarker study to identify the Acute risk of a Coronary Syndrome (BIOMArCS) was designed to evaluate whether repeated measuremen …
Stabilization patterns and variability of hs-CRP, NT-proBNP and ST2 during 1 year after acute coronary syndrome admission: results of the BIOMArCS study.
van den Berg VJ, Umans VAWM, Brankovic M, Oemrawsingh RM, Asselbergs FW, van der Harst P, Hoefer IE, Kietselaer B, Crijns HJGM, Lenderink T, Oude Ophuis AJ, van Schaik RH, Kardys I, Boersma E, Akkerhuis KM; BIOMArCS investigators. van den Berg VJ, et al. Clin Chem Lab Med. 2020 Nov 26;58(12):2099-2106. doi: 10.1515/cclm-2019-1320. Clin Chem Lab Med. 2020. PMID: 32383686 Free article.
In the current study, we report post-ACS kinetics and the variability of the hs-CRP, NT-proBNP and ST2. Methods BIOMArCS is a prospective, observational study with high frequency blood sampling during 1 year post-ACS. ...
In the current study, we report post-ACS kinetics and the variability of the hs-CRP, NT-proBNP and ST2. Methods BIOMArCS is a prospec …
Details on high frequency blood collection, data analysis, available material and patient characteristics in BIOMArCS.
Boersma E, Vroegindewey MM, van den Berg VJ, Asselbergs FW, van der Harst P, Kietselaer B, Lenderink T, Oude Ophuis AJ, Umans VAWM, de Winter RJ, Oemrawsingh RM, Akkerhuis KM. Boersma E, et al. Data Brief. 2019 Nov 5;27:104750. doi: 10.1016/j.dib.2019.104750. eCollection 2019 Dec. Data Brief. 2019. PMID: 31763405 Free PMC article.
The Biomarker Study to Identify the Acute Risk of a Coronary Syndrome (BIOMArCS) is a prospective, observational study that has been designed to study the evolution of blood biomarkers in post-acute coronary syndrome (ACS) patients. ...In addition, a detailed description o …
The Biomarker Study to Identify the Acute Risk of a Coronary Syndrome (BIOMArCS) is a prospective, observational study that has been …
Evolution of renal function and predictive value of serial renal assessments among patients with acute coronary syndrome: BIOMArCS study.
Brankovic M, Kardys I, van den Berg V, Oemrawsingh R, Asselbergs FW, van der Harst P, Hoefer IE, Liem A, Maas A, Ronner E, Schotborgh C, The SHK, Hoorn EJ, Boersma E, Akkerhuis KM; BIOMArCS investigators. Brankovic M, et al. Int J Cardiol. 2020 Jan 15;299:12-19. doi: 10.1016/j.ijcard.2019.07.052. Epub 2019 Jul 17. Int J Cardiol. 2020. PMID: 31353156 Free article.
We aimed to describe this evolution using serial measurements of creatinine, glomerular filtration rate [eGFR(Cr)] and cystatin C [CysC]. METHODS: From 844 ACS patients included in the BIOMArCS study, we analysed patient-specific longitudinal marker trajectories from the c …
We aimed to describe this evolution using serial measurements of creatinine, glomerular filtration rate [eGFR(Cr)] and cystatin C [CysC]. ME …
Intensive management of hyperglycaemia in acute coronary syndromes. Study design and rationale of the BIOMArCS 2 glucose trial.
de Mulder M, Umans VA, Stam F, Cornel JH, Oemrawsingh RM, Boersma E. de Mulder M, et al. Diabet Med. 2011 Oct;28(10):1168-75. doi: 10.1111/j.1464-5491.2011.03307.x. Diabet Med. 2011. PMID: 21480974 Clinical Trial.
Insulin has several characteristics that may potentially counteract these mechanisms. METHODS: The BIOMArCS programme is a multi-centre initiative and currently consists of three different studies. The effects of acute coronary syndrome on acute biomarkers washout are stud …
Insulin has several characteristics that may potentially counteract these mechanisms. METHODS: The BIOMArCS programme is a multi-cent …
Longitudinal profile of circulating endothelial cells in post-acute coronary syndrome patients.
de Bakker M, Kraan J, Akkerhuis KM, Oemrawsingh R, Asselbergs FW, Hoefer I, Kardys I, Boersma E. de Bakker M, et al. Biomarkers. 2023 Mar;28(2):152-159. doi: 10.1080/1354750X.2022.2162966. Epub 2023 Jan 8. Biomarkers. 2023. PMID: 36617894
Because of their close temporal relationship with vascular injury, longitudinal measurements of circulating endothelial cells (CECs) carry potential to improve individual risk assessment.MethodsWe conducted an explorative nested case-control study within our multicenter, prospect …
Because of their close temporal relationship with vascular injury, longitudinal measurements of circulating endothelial cells (CECs) carry p …
20 results