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Items: 1 to 20 of 101

1.

Screening of Preselected Libraries Targeting Mycobacterium abscessus for Drug Discovery.

Richter A, Strauch A, Chao J, Ko M, Av-Gay Y.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00828-18. doi: 10.1128/AAC.00828-18. Print 2018 Sep.

PMID:
30012760
2.

Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747.

Heinkel F, Shen L, Richard-Greenblatt M, Okon M, Bui JM, Gee CL, Gay LM, Alber T, Av-Gay Y, Gsponer J, McIntosh LP.

Structure. 2018 Jul 3;26(7):972-986.e6. doi: 10.1016/j.str.2018.04.018. Epub 2018 May 31.

PMID:
29861345
3.

Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides.

Laqua K, Klemm M, Richard-Greenblatt M, Richter A, Liebe L, Huang T, Lin S, Guardia A, Pérez-Herran E, Ballell L, Av-Gay Y, Imming P.

Bioorg Med Chem. 2018 Jul 23;26(12):3166-3190. doi: 10.1016/j.bmc.2018.04.045. Epub 2018 Apr 22.

PMID:
29706526
4.

Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages.

Wong D, Li W, Chao JD, Zhou P, Narula G, Tsui C, Ko M, Xie J, Martinez-Frailes C, Av-Gay Y.

Sci Rep. 2018 Jan 9;8(1):155. doi: 10.1038/s41598-017-18547-9.

5.

Nitric oxide inhalations in bronchiolitis: A pilot, randomized, double-blinded, controlled trial.

Tal A, Greenberg D, Av-Gay Y, Golan-Tripto I, Feinstein Y, Ben-Shimol S, Dagan R, Goldbart AD.

Pediatr Pulmonol. 2018 Jan;53(1):95-102. doi: 10.1002/ppul.23905. Epub 2017 Nov 27.

PMID:
29178284
6.

Genome Sequences of the Mycobacterium tuberculosis H37Rv-ptkA Deletion Mutant and Its Parental Strain.

Tsui CKM, Wong D, Narula G, Gardy JL, Hsiao WWH, Av-Gay Y.

Genome Announc. 2017 Nov 2;5(44). pii: e01156-17. doi: 10.1128/genomeA.01156-17.

7.
8.

Nitric oxide charged catheters as a potential strategy for prevention of hospital acquired infections.

Margel D, Mizrahi M, Regev-Shoshani G, Ko M, Moshe M, Ozalvo R, Shavit-Grievink L, Baniel J, Kedar D, Yossepowitch O, Lifshitz D, Nadu A, Greenberg D, Av-Gay Y.

PLoS One. 2017 Apr 14;12(4):e0174443. doi: 10.1371/journal.pone.0174443. eCollection 2017.

9.

Epigenetic Phosphorylation Control of Mycobacterium tuberculosis Infection and Persistence.

Richard-Greenblatt M, Av-Gay Y.

Microbiol Spectr. 2017 Mar;5(2). doi: 10.1128/microbiolspec.TBTB2-0005-2015. Review.

PMID:
28281439
10.

Aminorifamycins and Sporalactams Produced in Culture by a Micromonospora sp. Isolated from a Northeastern-Pacific Marine Sediment Are Potent Antibiotics.

Williams DE, Dalisay DS, Chen J, Polishchuck EA, Patrick BO, Narula G, Ko M, Av-Gay Y, Li H, Magarvey N, Andersen RJ.

Org Lett. 2017 Feb 17;19(4):766-769. doi: 10.1021/acs.orglett.6b03619. Epub 2017 Feb 6.

PMID:
28164711
11.

Intracellular Growth of Bacterial Pathogens: The Role of Secreted Effector Proteins in the Control of Phagocytosed Microorganisms.

Poirier V, Av-Gay Y.

Microbiol Spectr. 2015 Dec;3(6). doi: 10.1128/microbiolspec.VMBF-0003-2014. Review.

PMID:
27337278
12.

Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis.

Saini V, Cumming BM, Guidry L, Lamprecht DA, Adamson JH, Reddy VP, Chinta KC, Mazorodze JH, Glasgow JN, Richard-Greenblatt M, Gomez-Velasco A, Bach H, Av-Gay Y, Eoh H, Rhee K, Steyn AJC.

Cell Rep. 2016 Jan 26;14(3):572-585. doi: 10.1016/j.celrep.2015.12.056. Epub 2016 Jan 7.

13.

Development of an Intracellular Screen for New Compounds Able To Inhibit Mycobacterium tuberculosis Growth in Human Macrophages.

Sorrentino F, Gonzalez del Rio R, Zheng X, Presa Matilla J, Torres Gomez P, Martinez Hoyos M, Perez Herran ME, Mendoza Losana A, Av-Gay Y.

Antimicrob Agents Chemother. 2015 Oct 26;60(1):640-5. doi: 10.1128/AAC.01920-15. Print 2016 Jan.

14.

Phosphorylation of Mycobacterium tuberculosis protein tyrosine kinase A PtkA by Ser/Thr protein kinases.

Zhou P, Wong D, Li W, Xie J, Av-Gay Y.

Biochem Biophys Res Commun. 2015 Nov 13;467(2):421-6. doi: 10.1016/j.bbrc.2015.09.124. Epub 2015 Sep 26.

PMID:
26417687
15.

Regulation of Ergothioneine Biosynthesis and Its Effect on Mycobacterium tuberculosis Growth and Infectivity.

Richard-Greenblatt M, Bach H, Adamson J, Peña-Diaz S, Li W, Steyn AJ, Av-Gay Y.

J Biol Chem. 2015 Sep 18;290(38):23064-76. doi: 10.1074/jbc.M115.648642. Epub 2015 Jul 30.

16.

Immunoevasion and immunosuppression of the macrophage by Mycobacterium tuberculosis.

Hmama Z, Peña-Díaz S, Joseph S, Av-Gay Y.

Immunol Rev. 2015 Mar;264(1):220-32. doi: 10.1111/imr.12268. Review.

PMID:
25703562
17.

Phosphorylation control of protein tyrosine phosphatase A activity in Mycobacterium tuberculosis.

Zhou P, Li W, Wong D, Xie J, Av-Gay Y.

FEBS Lett. 2015 Jan 30;589(3):326-31. doi: 10.1016/j.febslet.2014.12.015. Epub 2014 Dec 20.

18.

Mycobacterium tuberculosis promotes anti-apoptotic activity of the macrophage by PtpA protein-dependent dephosphorylation of host GSK3α.

Poirier V, Bach H, Av-Gay Y.

J Biol Chem. 2014 Oct 17;289(42):29376-85. doi: 10.1074/jbc.M114.582502. Epub 2014 Sep 3.

19.

Microbial protein-tyrosine kinases.

Chao JD, Wong D, Av-Gay Y.

J Biol Chem. 2014 Apr 4;289(14):9463-72. doi: 10.1074/jbc.R113.520015. Epub 2014 Feb 19. Review.

20.

Mycobacterium tuberculosis nucleoside diphosphate kinase inactivates small GTPases leading to evasion of innate immunity.

Sun J, Singh V, Lau A, Stokes RW, Obregón-Henao A, Orme IM, Wong D, Av-Gay Y, Hmama Z.

PLoS Pathog. 2013;9(7):e1003499. doi: 10.1371/journal.ppat.1003499. Epub 2013 Jul 18.

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