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Items: 12


Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity.

Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ.

Nat Commun. 2019 Aug 21;10(1):3767. doi: 10.1038/s41467-019-11783-9.


ANIMA: Association network integration for multiscale analysis.

Deffur A, Wilkinson RJ, Mayosi BM, Mulder NM.

Version 2. Wellcome Open Res. 2018 Nov 14 [revised 2018 Jan 1];3:27. doi: 10.12688/wellcomeopenres.14073.3. eCollection 2018.


Poor Penetration of Antibiotics Into Pericardium in Pericardial Tuberculosis.

Shenje J, Ifeoma Adimora-Nweke F, Ross IL, Ntsekhe M, Wiesner L, Deffur A, McIlleron HM, Pasipanodya J, Gumbo T, Mayosi BM.

EBioMedicine. 2015 Sep 16;2(11):1640-9. doi: 10.1016/j.ebiom.2015.09.025. eCollection 2015 Nov.


A Compartmentalized Profibrotic Immune Response Characterizes Pericardial Tuberculosis, Irrespective of HIV-1 Infection.

Matthews K, Deffur A, Ntsekhe M, Syed F, Russell JB, Tibazarwa K, Wolske J, Brink J, Mayosi BM, Wilkinson RJ, Wilkinson KA.

Am J Respir Crit Care Med. 2015 Dec 15;192(12):1518-21. doi: 10.1164/rccm.201504-0683LE. No abstract available.


HIV-tuberculosis-associated immune reconstitution inflammatory syndrome is characterized by Toll-like receptor and inflammasome signalling.

Lai RPJ, Meintjes G, Wilkinson KA, Graham CM, Marais S, Van der Plas H, Deffur A, Schutz C, Bloom C, Munagala I, Anguiano E, Goliath R, Maartens G, Banchereau J, Chaussabel D, O'Garra A, Wilkinson RJ.

Nat Commun. 2015 Sep 24;6:8451. doi: 10.1038/ncomms9451.


Six host-range restricted poxviruses from three genera induce distinct gene expression profiles in an in vivo mouse model.

Offerman K, Deffur A, Carulei O, Wilkinson R, Douglass N, Williamson AL.

BMC Genomics. 2015 Jul 8;16:510. doi: 10.1186/s12864-015-1659-1.


Tricks to translating TB transcriptomics.

Deffur A, Wilkinson RJ, Coussens AK.

Ann Transl Med. 2015 May;3(Suppl 1):S43. doi: 10.3978/j.issn.2305-5839.2015.04.12.


Cytotoxic mediators in paradoxical HIV-tuberculosis immune reconstitution inflammatory syndrome.

Wilkinson KA, Walker NF, Meintjes G, Deffur A, Nicol MP, Skolimowska KH, Matthews K, Tadokera R, Seldon R, Maartens G, Rangaka MX, Besra GS, Wilkinson RJ.

J Immunol. 2015 Feb 15;194(4):1748-54. doi: 10.4049/jimmunol.1402105. Epub 2015 Jan 14.


Neutrophil-associated central nervous system inflammation in tuberculous meningitis immune reconstitution inflammatory syndrome.

Marais S, Wilkinson KA, Lesosky M, Coussens AK, Deffur A, Pepper DJ, Schutz C, Ismail Z, Meintjes G, Wilkinson RJ.

Clin Infect Dis. 2014 Dec 1;59(11):1638-47. doi: 10.1093/cid/ciu641. Epub 2014 Aug 8.


Prevalence, hemodynamics, and cytokine profile of effusive-constrictive pericarditis in patients with tuberculous pericardial effusion.

Ntsekhe M, Matthews K, Syed FF, Deffur A, Badri M, Commerford PJ, Gersh BJ, Wilkinson KA, Wilkinson RJ, Mayosi BM.

PLoS One. 2013 Oct 14;8(10):e77532. doi: 10.1371/journal.pone.0077532. eCollection 2013.


Co-infection with Mycobacterium tuberculosis and human immunodeficiency virus: an overview and motivation for systems approaches.

Deffur A, Mulder NJ, Wilkinson RJ.

Pathog Dis. 2013 Nov;69(2):101-13. doi: 10.1111/2049-632X.12060. Epub 2013 Jul 17. Review.


HIV-1 infection alters CD4+ memory T-cell phenotype at the site of disease in extrapulmonary tuberculosis.

Matthews K, Ntsekhe M, Syed F, Scriba T, Russell J, Tibazarwa K, Deffur A, Hanekom W, Mayosi BM, Wilkinson RJ, Wilkinson KA.

Eur J Immunol. 2012 Jan;42(1):147-57. doi: 10.1002/eji.201141927.

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