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J Arthroplasty. 2014 Jun;29(6):1098-100. doi: 10.1016/j.arth.2013.11.012. Epub 2013 Nov 25.

Aquacel surgical dressing reduces the rate of acute PJI following total joint arthroplasty: a case-control study.

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The Rothman Institute at Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.


An effort to prevent PJI has led to the development of antimicrobial dressings that support wound healing. We sought to determine whether Aquacel Surgical dressing independently reduces the rate of acute PJI following TJA. A single institution retrospective chart review of 903 consecutive cases who received the Aquacel Surgical dressing and 875 consecutive cases who received standard gauze dressing was conducted to determine the incidence of acute PJI (within 3 months). The incidence of acute PJI is 0.44% in the Aquacel dressing group compared to 1.7% in the standard gauze dressing group (P = 0.005). Multivariate analysis revealed that use of Aquacel dressing was an independent risk factor for reduction of PJI (odds ratio of 0.165, 95% confidence interval: 0.051-0.533). Aquacel Surgical dressing significantly reduces the incidence of acute PJI.


hip arthroplasty; knee arthroplasty; periprosthetic joint infection; wound dressing

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