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1987 1
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Page 1
[Azoles of then and now: a review].
Nocua-Báez LC, Uribe-Jerez P, Tarazona-Guaranga L, Robles R, Cortés JA. Nocua-Báez LC, et al. Rev Chilena Infectol. 2020 Jun;37(3):219-230. doi: 10.4067/s0716-10182020000300219. Rev Chilena Infectol. 2020. PMID: 32853312 Free article. Review. Spanish.
The adverse effects of the triazoles are less frequent compared to those caused by amphotericin B, the main ones being hepatics, gastrointestinals and cardiovasculars, such as the prolongation of the QT interval. ...
The adverse effects of the triazoles are less frequent compared to those caused by amphotericin B, the main ones being hepatic …
Zinc Oxide Nanoconjugates against Brain-Eating Amoebae.
Siddiqui R, Boghossian A, Akbar N, Jabri T, Aslam Z, Shah MR, Alharbi AM, Alfahemi H, Khan NA. Siddiqui R, et al. Antibiotics (Basel). 2022 Sep 20;11(10):1281. doi: 10.3390/antibiotics11101281. Antibiotics (Basel). 2022. PMID: 36289939 Free PMC article.
Herein, nanotechnology was used to conjugate Zinc oxide with Ampicillin, Ceftrixon, Naringin, Amphotericin B, and Quericitin, and the amoebicidal activity and host cell cytotoxicity of these resulting compounds were investigated. The compounds ZnO-CD-AMPi, ZnO-CD-CF …
Herein, nanotechnology was used to conjugate Zinc oxide with Ampicillin, Ceftrixon, Naringin, Amphotericin B, and Quericitin, …
Systemic antifungal agents. Drug interactions of clinical significance.
Albengres E, Le Louët H, Tillement JP. Albengres E, et al. Drug Saf. 1998 Feb;18(2):83-97. doi: 10.2165/00002018-199818020-00001. Drug Saf. 1998. PMID: 9512916 Review.
Amphotericin B and flucytosine mainly interact with other agents pharmacodynamically. ...Synergism is likely to occur when either QT interval-modifying drugs (e.g. terfenadine and astemizole) and drugs that induce hypokalaemia (e.g. amphotericin B …
Amphotericin B and flucytosine mainly interact with other agents pharmacodynamically. ...Synergism is likely to occur when eit …
Pharmacological options for Candida albicans Endocarditis at the roadblock with irrecoverable prosthetics and drug interactions: a case report and review of literature.
Sahra S, Javed A, Jahangir A, Thind SK. Sahra S, et al. BMC Infect Dis. 2023 May 8;23(1):304. doi: 10.1186/s12879-023-08267-z. BMC Infect Dis. 2023. PMID: 37158828 Free PMC article. Review.
Endocarditis from candidemia is a rare but possibly fatal complication. The efficacy of amphotericin and echinocandins for induction and azoles for suppression has been well studied. ...Suppression with fluconazole was contraindicated due to prolonged corrected QT ( …
Endocarditis from candidemia is a rare but possibly fatal complication. The efficacy of amphotericin and echinocandins for induction …
A randomized open label trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis.
Ngan NTT, Mai NTH, Tung NLN, Lan NPH, Tai LTH, Phu NH, Chau NVV, Binh TQ, Hung LQ, Beardsley J, White N, Lalloo D, Krysan D, Hope W, Geskus R, Wolbers M, Nhat LTH, Thwaites G, Kestelyn E, Day J. Ngan NTT, et al. Wellcome Open Res. 2019 Jan 22;4:8. doi: 10.12688/wellcomeopenres.15010.1. eCollection 2019. Wellcome Open Res. 2019. PMID: 30801037 Free PMC article.
International treatment guidelines recommend induction therapy with amphotericin B and flucytosine. This antifungal combination is most effective, but unfortunately flucytosine is expensive and unavailable where the burden of disease is greatest. Where unavailable, …
International treatment guidelines recommend induction therapy with amphotericin B and flucytosine. This antifungal combinatio …
Combination antifungal therapy for cryptococcal meningitis.
Day JN, Chau TTH, Wolbers M, Mai PP, Dung NT, Mai NH, Phu NH, Nghia HD, Phong ND, Thai CQ, Thai LH, Chuong LV, Sinh DX, Duong VA, Hoang TN, Diep PT, Campbell JI, Sieu TPM, Baker SG, Chau NVV, Hien TT, Lalloo DG, Farrar JJ. Day JN, et al. N Engl J Med. 2013 Apr 4;368(14):1291-1302. doi: 10.1056/NEJMoa1110404. N Engl J Med. 2013. PMID: 23550668 Free PMC article. Clinical Trial.
BACKGROUND: Combination antifungal therapy (amphotericin B deoxycholate and flucytosine) is the recommended treatment for cryptococcal meningitis but has not been shown to reduce mortality, as compared with amphotericin B alone. ...Rates of adverse eve …
BACKGROUND: Combination antifungal therapy (amphotericin B deoxycholate and flucytosine) is the recommended treatment for cryp …
Therapeutic Potential of Quercetin-Loaded Nanoemulsion against Experimental Visceral Leishmaniasis: In Vitro/Ex Vivo Studies and Mechanistic Insights.
Das SS, Dubey AK, Verma PRP, Singh SK, Singh SK. Das SS, et al. Mol Pharm. 2022 Sep 5;19(9):3367-3384. doi: 10.1021/acs.molpharmaceut.2c00492. Epub 2022 Aug 18. Mol Pharm. 2022. PMID: 35980291
Visceral leishmaniasis (VL) is one of the most fatal and neglected tropical diseases caused by Leishmania donovani (L. donovani). The applications of currently available chemotherapy (amphotericin B, miltefosine, and others) in VL treatment have been limited due to …
Visceral leishmaniasis (VL) is one of the most fatal and neglected tropical diseases caused by Leishmania donovani (L. donovani). The applic …
An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis.
Ngan NTT, Thanh Hoang Le N, Vi Vi NN, Van NTT, Mai NTH, Van Anh D, Trieu PH, Lan NPH, Phu NH, Chau NVV, Lalloo DG, Hope W, Beardsley J, White NJ, Geskus R, Thwaites GE, Krysan D, Tai LTH, Kestelyn E, Binh TQ, Hung LQ, Tung NLN, Day JN. Ngan NTT, et al. Elife. 2021 Sep 28;10:e68929. doi: 10.7554/eLife.68929. Elife. 2021. PMID: 34581270 Free PMC article. Clinical Trial.
The anticancer agent tamoxifen has synergistic anti-cryptococcal activity with amphotericin in vitro. It is off-patent, cheap, and widely available. ...METHODS: Open label randomized controlled trial. Participants received standard care - amphotericin combined with …
The anticancer agent tamoxifen has synergistic anti-cryptococcal activity with amphotericin in vitro. It is off-patent, cheap, and wi …
Differences in action potential and early afterdepolarization properties in LQT2 and LQT3 models of long QT syndrome.
Studenik CR, Zhou Z, January CT. Studenik CR, et al. Br J Pharmacol. 2001 Jan;132(1):85-92. doi: 10.1038/sj.bjp.0703770. Br J Pharmacol. 2001. PMID: 11156564 Free PMC article.
For the congenital disorders, their presentation and disease course are not identical. We studied two pharmacological models of long QT syndrome (LQT) to identify differences in cellular electrophysiological properties that may account for this. ...Single rabbit ventricula …
For the congenital disorders, their presentation and disease course are not identical. We studied two pharmacological models of long QT …
15 results