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See 1 citation in Am J Surg 2009:

Am J Surg. 2009 Oct;198(4):547-52. doi: 10.1016/j.amjsurg.2009.04.008.

Does magnetic resonance imaging accurately predict residual disease in breast cancer?

Author information

1
Department of Surgery, Mayo Clinic, 5777 E. Mayo Blvd., Phoenix, AZ 85054, USA. stucky.cheechee@mayo.edu

Abstract

BACKGROUND:

The accuracy of magnetic resonance imaging (MRI) in identifying residual disease after breast conservation therapy (BCT) is unclear.

METHOD:

Review of an institutional database identified patients with positive or close (<or=2 mm) margins undergoing MRI before re-excision. Histopathologic correlation was performed.

RESULTS:

Forty-three women underwent MRI after BCT. MRI suggested residual disease in 29 patients, of whom 20 (69%) had residual carcinoma pathologically. Nine patients had false-positive MRI as seen by benign pathology findings. Fourteen MRIs indicated no residual disease, of which 6 had residual disease pathologically. The sensitivity and positive predictive value of MRI was 77% and 69%, respectively. MRI conducted within 28 days of the original surgery was 85% sensitive. MRI performed after 28 days was 69% sensitive.

CONCLUSIONS:

MRI is able to detect residual disease among most patients undergoing re-excision. False-positive results may be caused by inflammatory processes that resemble residual disease.

PMID:
19800466
DOI:
10.1016/j.amjsurg.2009.04.008
[Indexed for MEDLINE]

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