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Lipid signalling in the mesolimbic dopamine pathway.

Fulton S, Alquier T.

Neuropsychopharmacology. 2019 Jan;44(1):221-222. doi: 10.1038/s41386-018-0188-4. Epub 2018 Aug 24. No abstract available.


Nucleus accumbens inflammation mediates anxiodepressive behavior and compulsive sucrose seeking elicited by saturated dietary fat.

Décarie-Spain L, Sharma S, Hryhorczuk C, Issa-Garcia V, Barker PA, Arbour N, Alquier T, Fulton S.

Mol Metab. 2018 Apr;10:1-13. doi: 10.1016/j.molmet.2018.01.018. Epub 2018 Jan 31.


Considerations and guidelines for mouse metabolic phenotyping in diabetes research.

Alquier T, Poitout V.

Diabetologia. 2018 Mar;61(3):526-538. doi: 10.1007/s00125-017-4495-9. Epub 2017 Nov 16. Review.


Oleic Acid in the Ventral Tegmental Area Inhibits Feeding, Food Reward, and Dopamine Tone.

Hryhorczuk C, Sheng Z, Décarie-Spain L, Giguère N, Ducrot C, Trudeau LÉ, Routh VH, Alquier T, Fulton S.

Neuropsychopharmacology. 2018 Feb;43(3):607-616. doi: 10.1038/npp.2017.203. Epub 2017 Aug 31.


Saturated high-fat feeding independent of obesity alters hypothalamus-pituitary-adrenal axis function but not anxiety-like behaviour.

Hryhorczuk C, Décarie-Spain L, Sharma S, Daneault C, Rosiers CD, Alquier T, Fulton S.

Psychoneuroendocrinology. 2017 Sep;83:142-149. doi: 10.1016/j.psyneuen.2017.06.002. Epub 2017 Jun 10.


Insulin Inhibits Nrf2 Gene Expression via Heterogeneous Nuclear Ribonucleoprotein F/K in Diabetic Mice.

Ghosh A, Abdo S, Zhao S, Wu CH, Shi Y, Lo CS, Chenier I, Alquier T, Filep JG, Ingelfinger JR, Zhang SL, Chan JSD.

Endocrinology. 2017 Apr 1;158(4):903-919. doi: 10.1210/en.2016-1576.


α/β-Hydrolase Domain 6 in the Ventromedial Hypothalamus Controls Energy Metabolism Flexibility.

Fisette A, Tobin S, Décarie-Spain L, Bouyakdan K, Peyot ML, Madiraju SRM, Prentki M, Fulton S, Alquier T.

Cell Rep. 2016 Oct 25;17(5):1217-1226. doi: 10.1016/j.celrep.2016.10.004.


DBI/ACBP loss-of-function does not affect anxiety-like behaviour but reduces anxiolytic responses to diazepam in mice.

Budry L, Bouyakdan K, Tobin S, Rodaros D, Marcher AB, Mandrup S, Fulton S, Alquier T.

Behav Brain Res. 2016 Oct 15;313:201-7. doi: 10.1016/j.bbr.2016.06.052. Epub 2016 Jun 27.


Central Agonism of GPR120 Acutely Inhibits Food Intake and Food Reward and Chronically Suppresses Anxiety-Like Behavior in Mice.

Auguste S, Fisette A, Fernandes MF, Hryhorczuk C, Poitout V, Alquier T, Fulton S.

Int J Neuropsychopharmacol. 2016 Jul 5;19(7). pii: pyw014. doi: 10.1093/ijnp/pyw014. Print 2016 Jul.


PGC-1 coactivators in β-cells regulate lipid metabolism and are essential for insulin secretion coupled to fatty acids.

Oropeza D, Jouvet N, Bouyakdan K, Perron G, Ringuette LJ, Philipson LH, Kiss RS, Poitout V, Alquier T, Estall JL.

Mol Metab. 2015 Aug 14;4(11):811-22. doi: 10.1016/j.molmet.2015.08.001. eCollection 2015 Nov.


AstroGenesis: And there was leptin on the sixth day.

Fisette A, Alquier T.

Mol Metab. 2015 Oct 3;4(11):755-7. doi: 10.1016/j.molmet.2015.09.009. eCollection 2015 Nov. No abstract available.


Leptin Suppresses the Rewarding Effects of Running via STAT3 Signaling in Dopamine Neurons.

Fernandes MF, Matthys D, Hryhorczuk C, Sharma S, Mogra S, Alquier T, Fulton S.

Cell Metab. 2015 Oct 6;22(4):741-9. doi: 10.1016/j.cmet.2015.08.003. Epub 2015 Sep 1.


Dampened Mesolimbic Dopamine Function and Signaling by Saturated but not Monounsaturated Dietary Lipids.

Hryhorczuk C, Florea M, Rodaros D, Poirier I, Daneault C, Des Rosiers C, Arvanitogiannis A, Alquier T, Fulton S.

Neuropsychopharmacology. 2016 Feb;41(3):811-21. doi: 10.1038/npp.2015.207. Epub 2015 Jul 14.


Phenotypic Characterization of MIP-CreERT1Lphi Mice With Transgene-Driven Islet Expression of Human Growth Hormone.

Oropeza D, Jouvet N, Budry L, Campbell JE, Bouyakdan K, Lacombe J, Perron G, Bergeron V, Neuman JC, Brar HK, Fenske RJ, Meunier C, Sczelecki S, Kimple ME, Drucker DJ, Screaton RA, Poitout V, Ferron M, Alquier T, Estall JL.

Diabetes. 2015 Nov;64(11):3798-807. doi: 10.2337/db15-0272. Epub 2015 Jul 7.


An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion.

Priyadarshini M, Villa SR, Fuller M, Wicksteed B, Mackay CR, Alquier T, Poitout V, Mancebo H, Mirmira RG, Gilchrist A, Layden BT.

Mol Endocrinol. 2015 Jul;29(7):1055-66. doi: 10.1210/me.2015-1007. Epub 2015 Jun 15.


A novel role for central ACBP/DBI as a regulator of long-chain fatty acid metabolism in astrocytes.

Bouyakdan K, Taïb B, Budry L, Zhao S, Rodaros D, Neess D, Mandrup S, Faergeman NJ, Alquier T.

J Neurochem. 2015 Apr;133(2):253-65. doi: 10.1111/jnc.13035. Epub 2015 Feb 6.


Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice.

Fergusson G, Ethier M, Guévremont M, Chrétien C, Attané C, Joly E, Fioramonti X, Prentki M, Poitout V, Alquier T.

Mol Metab. 2014 Sep 28;3(9):848-54. doi: 10.1016/j.molmet.2014.09.006. eCollection 2014 Dec.


Deletion of apoptosis signal-regulating kinase 1 (ASK1) protects pancreatic beta-cells from stress-induced death but not from glucose homeostasis alterations under pro-inflammatory conditions.

Pepin E, Higa A, Schuster-Klein C, Bernard C, Sulpice T, Guardiola B, Chevet E, Alquier T.

PLoS One. 2014 Nov 10;9(11):e112714. doi: 10.1371/journal.pone.0112714. eCollection 2014.


Glucose regulates hypothalamic long-chain fatty acid metabolism via AMP-activated kinase (AMPK) in neurons and astrocytes.

Taïb B, Bouyakdan K, Hryhorczuk C, Rodaros D, Fulton S, Alquier T.

J Biol Chem. 2013 Dec 27;288(52):37216-29. doi: 10.1074/jbc.M113.506238. Epub 2013 Nov 15.


Fatty acid receptor Gpr40 mediates neuromicrovascular degeneration induced by transarachidonic acids in rodents.

Honoré JC, Kooli A, Hamel D, Alquier T, Rivera JC, Quiniou C, Hou X, Kermorvant-Duchemin E, Hardy P, Poitout V, Chemtob S.

Arterioscler Thromb Vasc Biol. 2013 May;33(5):954-61. doi: 10.1161/ATVBAHA.112.300943. Epub 2013 Mar 21.


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