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Items: 14

1.

A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2.

Garland W, Comet I, Wu M, Radzisheuskaya A, Rib L, Vitting-Seerup K, Lloret-Llinares M, Sandelin A, Helin K, Jensen TH.

Cell Rep. 2019 Nov 12;29(7):1800-1811.e6. doi: 10.1016/j.celrep.2019.10.011.

PMID:
31722198
2.

PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia.

Radzisheuskaya A, Shliaha PV, Grinev V, Lorenzini E, Kovalchuk S, Shlyueva D, Gorshkov V, Hendrickson RC, Jensen ON, Helin K.

Nat Struct Mol Biol. 2019 Nov;26(11):999-1012. doi: 10.1038/s41594-019-0313-z. Epub 2019 Oct 14.

PMID:
31611688
3.

Distinct Molecular Trajectories Converge to Induce Naive Pluripotency.

Stuart HT, Stirparo GG, Lohoff T, Bates LE, Kinoshita M, Lim CY, Sousa EJ, Maskalenka K, Radzisheuskaya A, Malcolm AA, Alves MRP, Lloyd RL, Nestorowa S, Humphreys P, Mansfield W, Reik W, Bertone P, Nichols J, Göttgens B, Silva JCR.

Cell Stem Cell. 2019 Sep 5;25(3):388-406.e8. doi: 10.1016/j.stem.2019.07.009. Epub 2019 Aug 15.

4.

Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression.

Radzisheuskaya A, Shlyueva D, Müller I, Helin K.

Nucleic Acids Res. 2016 Oct 14;44(18):e141. Epub 2016 Jun 28.

5.

Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development.

Pedersen MT, Kooistra SM, Radzisheuskaya A, Laugesen A, Johansen JV, Hayward DG, Nilsson J, Agger K, Helin K.

EMBO J. 2016 Jul 15;35(14):1550-64. doi: 10.15252/embj.201593317. Epub 2016 Jun 6.

6.

MBD3/NuRD Facilitates Induction of Pluripotency in a Context-Dependent Manner.

Dos Santos RL, Tosti L, Radzisheuskaya A, Caballero IM, Kaji K, Hendrich B, Silva JCR.

Cell Stem Cell. 2014 Sep 4;15(3):392. doi: 10.1016/j.stem.2014.08.005. Epub 2014 Sep 4. No abstract available.

7.

MBD3/NuRD facilitates induction of pluripotency in a context-dependent manner.

dos Santos RL, Tosti L, Radzisheuskaya A, Caballero IM, Kaji K, Hendrich B, Silva JC.

Cell Stem Cell. 2014 Jul 3;15(1):102-10. doi: 10.1016/j.stem.2014.04.019. Epub 2014 May 15. Erratum in: Cell Stem Cell. 2014 Sep 4;15(3):392.

8.

Citrullination regulates pluripotency and histone H1 binding to chromatin.

Christophorou MA, Castelo-Branco G, Halley-Stott RP, Oliveira CS, Loos R, Radzisheuskaya A, Mowen KA, Bertone P, Silva JC, Zernicka-Goetz M, Nielsen ML, Gurdon JB, Kouzarides T.

Nature. 2014 Mar 6;507(7490):104-8. doi: 10.1038/nature12942. Epub 2014 Jan 26.

9.

NANOG amplifies STAT3 activation and they synergistically induce the naive pluripotent program.

Stuart HT, van Oosten AL, Radzisheuskaya A, Martello G, Miller A, Dietmann S, Nichols J, Silva JC.

Curr Biol. 2014 Feb 3;24(3):340-6. doi: 10.1016/j.cub.2013.12.040. Epub 2014 Jan 23.

10.

Do all roads lead to Oct4? the emerging concepts of induced pluripotency.

Radzisheuskaya A, Silva JC.

Trends Cell Biol. 2014 May;24(5):275-84. doi: 10.1016/j.tcb.2013.11.010. Epub 2013 Dec 23. Review.

11.

A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages.

Radzisheuskaya A, Chia Gle B, dos Santos RL, Theunissen TW, Castro LF, Nichols J, Silva JC.

Nat Cell Biol. 2013 Jun;15(6):579-90. doi: 10.1038/ncb2742. Epub 2013 Apr 30.

12.

Tcf15 primes pluripotent cells for differentiation.

Davies OR, Lin CY, Radzisheuskaya A, Zhou X, Taube J, Blin G, Waterhouse A, Smith AJ, Lowell S.

Cell Rep. 2013 Feb 21;3(2):472-84. doi: 10.1016/j.celrep.2013.01.017. Epub 2013 Feb 7.

13.

Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency.

Pasque V, Radzisheuskaya A, Gillich A, Halley-Stott RP, Panamarova M, Zernicka-Goetz M, Surani MA, Silva JC.

J Cell Sci. 2012 Dec 15;125(Pt 24):6094-104. doi: 10.1242/jcs.113019. Epub 2012 Oct 17.

14.

Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain.

Theunissen TW, Costa Y, Radzisheuskaya A, van Oosten AL, Lavial F, Pain B, Castro LF, Silva JC.

Development. 2011 Nov;138(22):4853-65. doi: 10.1242/dev.068775.

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