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DNA methylation dynamics in human induced pluripotent stem cells over time.
Nishino K, Toyoda M, Yamazaki-Inoue M, Fukawatase Y, Chikazawa E, Sakaguchi H, Akutsu H, Umezawa A.
PLoS Genet. 2011 May;7(5):e1002085. doi: 10.1371/journal.pgen.1002085. Epub 2011 May 26.
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Preferential localization of SSEA-4 in interfaces between blastomeres of mouse preimplantaion embryos.
Sato B, Katagiri YU, Miyado K, Akutsu H, Miyagawa Y, Horiuchi Y, Nakajima H, Okita H, Umezawa A, Hata J, Fujimoto J, Toshimori K, Kiyokawa N.
Biochem Biophys Res Commun. 2007 Dec 28;364(4):838-43. doi: 10.1016/j.bbrc.2007.10.093. Epub 2007 Oct 26.
[Osteogenesis and chondrogenesis from a stem cell source].
Umezawa A, Akutsu H.
Clin Calcium. 2008 Dec;18(12):1721-7. doi: CliCa081217211727. Review. Japanese.
Mesenchymal to embryonic incomplete transition of human cells by chimeric OCT4/3 (POU5F1) with physiological co-activator EWS.
Makino H, Toyoda M, Matsumoto K, Saito H, Nishino K, Fukawatase Y, Machida M, Akutsu H, Uyama T, Miyagawa Y, Okita H, Kiyokawa N, Fujino T, Ishikawa Y, Nakamura T, Umezawa A.
Exp Cell Res. 2009 Oct 1;315(16):2727-40. doi: 10.1016/j.yexcr.2009.06.016. Epub 2009 Jun 24.
Maintenance of pluripotency and self-renewal ability of mouse embryonic stem cells in the absence of tetraspanin CD9.
Akutsu H, Miura T, Machida M, Birumachi J, Hamada A, Yamada M, Sullivan S, Miyado K, Umezawa A.
Differentiation. 2009 Sep-Oct;78(2-3):137-42. doi: 10.1016/j.diff.2009.08.005. Epub 2009 Aug 28.
Efficient reprogramming of human and mouse primary extra-embryonic cells to pluripotent stem cells.
Nagata S, Toyoda M, Yamaguchi S, Hirano K, Makino H, Nishino K, Miyagawa Y, Okita H, Kiyokawa N, Nakagawa M, Yamanaka S, Akutsu H, Umezawa A, Tada T.
Genes Cells. 2009 Dec;14(12):1395-404. doi: 10.1111/j.1365-2443.2009.01356.x. Epub 2009 Nov 13.
Involvement of a novel preimplantation-specific gene encoding the high mobility group box protein Hmgpi in early embryonic development.
Yamada M, Hamatani T, Akutsu H, Chikazawa N, Kuji N, Yoshimura Y, Umezawa A.
Hum Mol Genet. 2010 Feb 1;19(3):480-93. doi: 10.1093/hmg/ddp512. Epub 2009 Nov 14.
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells.
Stadtfeld M, Apostolou E, Akutsu H, Fukuda A, Follett P, Natesan S, Kono T, Shioda T, Hochedlinger K.
Nature. 2010 May 13;465(7295):175-81. doi: 10.1038/nature09017. Epub 2010 Apr 25.
Enhanced effects of secreted soluble factor preserve better pluripotent state of embryonic stem cell culture in a membrane-based compartmentalized micro-bioreactor.
Chowdhury MM, Katsuda T, Montagne K, Kimura H, Kojima N, Akutsu H, Ochiya T, Fujii T, Sakai Y.
Biomed Microdevices. 2010 Dec;12(6):1097-105. doi: 10.1007/s10544-010-9464-8.
Chemical inhibition of sulfation accelerates neural differentiation of mouse embryonic stem cells and human induced pluripotent stem cells.
Sasaki N, Hirano T, Kobayashi K, Toyoda M, Miyakawa Y, Okita H, Kiyokawa N, Akutsu H, Umezawa A, Nishihara S.
Biochem Biophys Res Commun. 2010 Oct 22;401(3):480-6. doi: 10.1016/j.bbrc.2010.09.085. Epub 2010 Sep 25.
Defining hypo-methylated regions of stem cell-specific promoters in human iPS cells derived from extra-embryonic amnions and lung fibroblasts.
Nishino K, Toyoda M, Yamazaki-Inoue M, Makino H, Fukawatase Y, Chikazawa E, Takahashi Y, Miyagawa Y, Okita H, Kiyokawa N, Akutsu H, Umezawa A.
PLoS One. 2010 Sep 27;5(9):e13017. doi: 10.1371/journal.pone.0013017.
Efficient generation of hepatoblasts from human ES cells and iPS cells by transient overexpression of homeobox gene HEX.
Inamura M, Kawabata K, Takayama K, Tashiro K, Sakurai F, Katayama K, Toyoda M, Akutsu H, Miyagawa Y, Okita H, Kiyokawa N, Umezawa A, Hayakawa T, Furue MK, Mizuguchi H.
Mol Ther. 2011 Feb;19(2):400-7. doi: 10.1038/mt.2010.241. Epub 2010 Nov 23.
Lectin microarray analysis of pluripotent and multipotent stem cells.
Toyoda M, Yamazaki-Inoue M, Itakura Y, Kuno A, Ogawa T, Yamada M, Akutsu H, Takahashi Y, Kanzaki S, Narimatsu H, Hirabayashi J, Umezawa A.
Genes Cells. 2011 Jan;16(1):1-11. doi: 10.1111/j.1365-2443.2010.01459.x. Epub 2010 Dec 13.
A distinct role for Pin1 in the induction and maintenance of pluripotency.
Nishi M, Akutsu H, Masui S, Kondo A, Nagashima Y, Kimura H, Perrem K, Shigeri Y, Toyoda M, Okayama A, Hirano H, Umezawa A, Yamamoto N, Lee SW, Ryo A.
J Biol Chem. 2011 Apr 1;286(13):11593-603. doi: 10.1074/jbc.M110.187989. Epub 2011 Feb 4.
Glycome diagnosis of human induced pluripotent stem cells using lectin microarray.
Tateno H, Toyota M, Saito S, Onuma Y, Ito Y, Hiemori K, Fukumura M, Matsushima A, Nakanishi M, Ohnuma K, Akutsu H, Umezawa A, Horimoto K, Hirabayashi J, Asashima M.
J Biol Chem. 2011 Jun 10;286(23):20345-53. doi: 10.1074/jbc.M111.231274. Epub 2011 Apr 6.
Early senescence is not an inevitable fate of human-induced pluripotent stem-derived cells.
Gokoh M, Nishio M, Nakamura N, Matsuyama S, Nakahara M, Suzuki S, Mitsumoto M, Akutsu H, Umezawa A, Yasuda K, Yuo A, Saeki K.
Cell Reprogram. 2011 Aug;13(4):361-70. doi: 10.1089/cell.2011.0004. Epub 2011 Jun 30.
Feeder-free and serum-free production of hepatocytes, cholangiocytes, and their proliferating progenitors from human pluripotent stem cells: application to liver-specific functional and cytotoxic assays.
Nakamura N, Saeki K, Mitsumoto M, Matsuyama S, Nishio M, Saeki K, Hasegawa M, Miyagawa Y, Ohkita H, Kiyokawa N, Toyoda M, Akutsu H, Umezawa A, Yuo A.
Cell Reprogram. 2012 Apr;14(2):171-85. doi: 10.1089/cell.2011.0064. Epub 2012 Mar 2.
Investigating cellular identity and manipulating cell fate using induced pluripotent stem cells.
Sugawara T, Nishino K, Umezawa A, Akutsu H.
Stem Cell Res Ther. 2012 Mar 8;3(2):8. doi: 10.1186/scrt99. Review.
Production of functional classical brown adipocytes from human pluripotent stem cells using specific hemopoietin cocktail without gene transfer.
Nishio M, Yoneshiro T, Nakahara M, Suzuki S, Saeki K, Hasegawa M, Kawai Y, Akutsu H, Umezawa A, Yasuda K, Tobe K, Yuo A, Kubota K, Saito M, Saeki K.
Cell Metab. 2012 Sep 5;16(3):394-406. doi: 10.1016/j.cmet.2012.08.001. Erratum in: Cell Metab. 2012 Nov 7;16(5):684-5.
Spatiotemporally controlled delivery of soluble factors for stem cell differentiation.
Kawada J, Kimura H, Akutsu H, Sakai Y, Fujii T.
Lab Chip. 2012 Nov 7;12(21):4508-15. doi: 10.1039/c2lc40268h.
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