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Year | Number of Results |
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2005 | 1 |
2008 | 2 |
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Page 1
Novel sulfamoyl benzamides as selective CB(2) agonists with improved in vitro metabolic stability.
Bioorg Med Chem Lett. 2010 Jan 1;20(1):387-91. doi: 10.1016/j.bmcl.2009.10.062. Epub 2009 Oct 17.
Bioorg Med Chem Lett. 2010.
PMID: 19919895
Potent, orally bioavailable delta opioid receptor agonists for the treatment of pain: discovery of N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide (ADL5859).
Le Bourdonnec B, Windh RT, Ajello CW, Leister LK, Gu M, Chu GH, Tuthill PA, Barker WM, Koblish M, Wiant DD, Graczyk TM, Belanger S, Cassel JA, Feschenko MS, Brogdon BL, Smith SA, Christ DD, Derelanko MJ, Kutz S, Little PJ, DeHaven RN, DeHaven-Hudkins DL, Dolle RE.
Le Bourdonnec B, et al. Among authors: ajello cw.
J Med Chem. 2008 Oct 9;51(19):5893-6. doi: 10.1021/jm8008986. Epub 2008 Sep 13.
J Med Chem. 2008.
PMID: 18788723
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Spirocyclic delta opioid receptor agonists for the treatment of pain: discovery of N,N-diethyl-3-hydroxy-4-(spiro[chromene-2,4'-piperidine]-4-yl) benzamide (ADL5747).
Le Bourdonnec B, Windh RT, Leister LK, Zhou QJ, Ajello CW, Gu M, Chu GH, Tuthill PA, Barker WM, Koblish M, Wiant DD, Graczyk TM, Belanger S, Cassel JA, Feschenko MS, Brogdon BL, Smith SA, Derelanko MJ, Kutz S, Little PJ, DeHaven RN, DeHaven-Hudkins DL, Dolle RE.
Le Bourdonnec B, et al. Among authors: ajello cw.
J Med Chem. 2009 Sep 24;52(18):5685-702. doi: 10.1021/jm900773n.
J Med Chem. 2009.
PMID: 19694468
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Arylacetamide kappa opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity.
Le Bourdonnec B, Ajello CW, Seida PR, Susnow RG, Cassel JA, Belanger S, Stabley GJ, DeHaven RN, DeHaven-Hudkins DL, Dolle RE.
Le Bourdonnec B, et al. Among authors: ajello cw.
Bioorg Med Chem Lett. 2005 May 16;15(10):2647-52. doi: 10.1016/j.bmcl.2005.03.020.
Bioorg Med Chem Lett. 2005.
PMID: 15863335
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CB2 selective sulfamoyl benzamides: optimization of the amide functionality.
Goodman AJ, Ajello CW, Worm K, Le Bourdonnec B, Savolainen MA, O'Hare H, Cassel JA, Stabley GJ, Dehaven RN, Labuda CJ, Koblish M, Little PJ, Brogdon BL, Smith SA, Dolle RE.
Goodman AJ, et al. Among authors: ajello cw.
Bioorg Med Chem Lett. 2009 Jan 15;19(2):309-13. doi: 10.1016/j.bmcl.2008.11.091. Epub 2008 Nov 27.
Bioorg Med Chem Lett. 2009.
PMID: 19091565
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Design and Synthesis of Imidazopyrimidine Derivatives as Potent iNOS Dimerization Inhibitors.
Chu GH, Le Bourdonnec B, Gu M, Ajello CW, Leister LK, Sellitto I, Cassel JA, Tuthill PA, O' Hare H, Dehaven RN, Dolle RE.
Chu GH, et al. Among authors: ajello cw.
Open Med Chem J. 2009 Nov 18;3:8-13. doi: 10.2174/1874104500903010008.
Open Med Chem J. 2009.
PMID: 19966921
Free PMC article.
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Nascent structure-activity relationship study of a diastereomeric series of kappa opioid receptor antagonists derived from CJ-15,208.
Dolle RE, Michaut M, Martinez-Teipel B, Seida PR, Ajello CW, Muller AL, DeHaven RN, Carroll PJ.
Dolle RE, et al. Among authors: ajello cw.
Bioorg Med Chem Lett. 2009 Jul 1;19(13):3647-50. doi: 10.1016/j.bmcl.2009.04.105. Epub 2009 May 3.
Bioorg Med Chem Lett. 2009.
PMID: 19464172
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