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Aging (Albany NY). 2010 Aug;2(8):461-70.

Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level.

Author information

1
Department of Biology, Concordia University, Montreal, Quebec H4B 1R6, Canada.

Abstract

We recently found that lithocholic acid (LCA), a bile acid, extends yeast longevity. Unlike mammals, yeast do not synthesize bile acids. We therefore propose that bile acids released into the environment by mammals may act as interspecies chemical signals providing longevity benefits to yeast and, perhaps, other species within an ecosystem.

PMID:
20693605
PMCID:
PMC2954037
DOI:
10.18632/aging.100186
[Indexed for MEDLINE]
Free PMC Article

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