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Autophagy. 2016;12(3):588-9. doi: 10.1080/15548627.2015.1106667.

Adipose tissue autophagy status in obesity: Expression and flux--two faces of the picture.

Author information

1
a INSERM UMRS 1166, Sorbonne University, Pierre & Marie Curie, Institute of Cardiometabolism and Nutrition, Pitié-Salpetriere Hospital , Paris , France.

Abstract

In the context of elevated prevalence of obesity-associated metabolic diseases in the human population worldwide, interest in the autophagy degradation pathway is increasing, due to close links with energy metabolism, nutritional state, and inflammation. Here we highlight recent data focusing on adipose tissue which demonstrate alterations in fat cell autophagic flux in human obesity.

KEYWORDS:

DAPK2; LC3-II; adipocyte; bariatric surgery; obesity

PMID:
26565777
PMCID:
PMC4835957
DOI:
10.1080/15548627.2015.1106667
[Indexed for MEDLINE]
Free PMC Article

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