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Items: 1 to 20 of 102


AKT Inhibition Modulates H3K4 Demethylase Levels in PTEN-Null Prostate Cancer.

Khan MI, Hamid A, Rath S, Ateeq B, Khan Q, Siddiqui IA, Adhami VM, Choudhry H, Zamzami MA, Mukhtar H.

Mol Cancer Ther. 2018 Nov 16. doi: 10.1158/1535-7163.MCT-18-0141. [Epub ahead of print]


Pro-proliferative function of adaptor protein GRB10 in prostate carcinoma.

Khan MI, Al Johani A, Hamid A, Ateeq B, Manzar N, Adhami VM, Lall RK, Rath S, Sechi M, Siddiqui IA, Choudhry H, Zamzami MA, Havighurst TC, Huang W, Ntambi JM, Mukhtar H.

FASEB J. 2018 Oct 31:fj201800265RR. doi: 10.1096/fj.201800265RR. [Epub ahead of print]


Chitosan-based nanoformulated (-)-epigallocatechin-3-gallate (EGCG) modulates human keratinocyte-induced responses and alleviates imiquimod-induced murine psoriasiform dermatitis.

Chamcheu JC, Siddiqui IA, Adhami VM, Esnault S, Bharali DJ, Babatunde AS, Adame S, Massey RJ, Wood GS, Longley BJ, Mousa SA, Mukhtar H.

Int J Nanomedicine. 2018 Jul 20;13:4189-4206. doi: 10.2147/IJN.S165966. eCollection 2018.


Nummularic acid, a triterpenoid, from the medicinal plant Fraxinus xanthoxyloides, induces energy crisis to suppress growth of prostate cancer cells.

Younis T, Khan MI, Khan MR, Rasul A, Majid M, Adhami VM, Mukhtar H.

Mol Carcinog. 2018 Oct;57(10):1267-1277. doi: 10.1002/mc.22841. Epub 2018 Jun 5.


Targeting epigenome with dietary nutrients in cancer: Current advances and future challenges.

Khan MI, Rath S, Adhami VM, Mukhtar H.

Pharmacol Res. 2018 Mar;129:375-387. doi: 10.1016/j.phrs.2017.12.008. Epub 2017 Dec 9. Review.


Hypoxia driven glycation: Mechanisms and therapeutic opportunities.

Khan MI, Rath S, Adhami VM, Mukhtar H.

Semin Cancer Biol. 2018 Apr;49:75-82. doi: 10.1016/j.semcancer.2017.05.008. Epub 2017 May 22. Review.


Targeted nanoparticles encapsulating (-)-epigallocatechin-3-gallate for prostate cancer prevention and therapy.

Sanna V, Singh CK, Jashari R, Adhami VM, Chamcheu JC, Rady I, Sechi M, Mukhtar H, Siddiqui IA.

Sci Rep. 2017 Feb 1;7:41573. doi: 10.1038/srep41573.


Fisetin Enhances Chemotherapeutic Effect of Cabazitaxel against Human Prostate Cancer Cells.

Mukhtar E, Adhami VM, Siddiqui IA, Verma AK, Mukhtar H.

Mol Cancer Ther. 2016 Dec;15(12):2863-2874. Epub 2016 Oct 7.


Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features In Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice.

Chamcheu JC, Adhami VM, Esnault S, Sechi M, Siddiqui IA, Satyshur KA, Syed DN, Dodwad SM, Chaves-Rodriquez MI, Longley BJ, Wood GS, Mukhtar H.

Antioxid Redox Signal. 2017 Jan 10;26(2):49-69. doi: 10.1089/ars.2016.6769. Epub 2016 Oct 4.


Dietary flavonoid fisetin increases abundance of high-molecular-mass hyaluronan conferring resistance to prostate oncogenesis.

Lall RK, Syed DN, Khan MI, Adhami VM, Gong Y, Lucey JA, Mukhtar H.

Carcinogenesis. 2016 Sep;37(9):918-928. doi: 10.1093/carcin/bgw071. Epub 2016 Jun 22.


Nutrition in the cause and prevention of cancer: An update.

Adhami VM, Mukhtar H.

Mol Nutr Food Res. 2016 Jun;60(6):1226-7. doi: 10.1002/mnfr.201670064. No abstract available.


Exploring the molecular targets of dietary flavonoid fisetin in cancer.

Syed DN, Adhami VM, Khan N, Khan MI, Mukhtar H.

Semin Cancer Biol. 2016 Oct;40-41:130-140. doi: 10.1016/j.semcancer.2016.04.003. Epub 2016 May 6. Review.


Dietary flavonoid fisetin for cancer prevention and treatment.

Lall RK, Adhami VM, Mukhtar H.

Mol Nutr Food Res. 2016 Jun;60(6):1396-405. doi: 10.1002/mnfr.201600025. Epub 2016 May 6. Review.


Upregulation of PI3K/AKT/mTOR, FABP5 and PPARβ/δ in Human Psoriasis and Imiquimod-induced Murine Psoriasiform Dermatitis Model.

Chamcheu JC, Chaves-Rodriquez MI, Adhami VM, Siddiqui IA, Wood GS, Longley BJ, Mukhtar H.

Acta Derm Venereol. 2016 Aug 23;96(6):854-6. doi: 10.2340/00015555-2359. No abstract available.


The pentacyclic triterpenoid, plectranthoic acid, a novel activator of AMPK induces apoptotic death in prostate cancer cells.

Akhtar N, Syed DN, Khan MI, Adhami VM, Mirza B, Mukhtar H.

Oncotarget. 2016 Jan 26;7(4):3819-31. doi: 10.18632/oncotarget.6625.


Dietary flavonoid fisetin binds to β-tubulin and disrupts microtubule dynamics in prostate cancer cells.

Mukhtar E, Adhami VM, Sechi M, Mukhtar H.

Cancer Lett. 2015 Oct 28;367(2):173-83. doi: 10.1016/j.canlet.2015.07.030. Epub 2015 Jul 30.


Dietary polyphenols in prevention and treatment of prostate cancer.

Lall RK, Syed DN, Adhami VM, Khan MI, Mukhtar H.

Int J Mol Sci. 2015 Feb 3;16(2):3350-76. doi: 10.3390/ijms16023350. Review.


Prodifferentiation, anti-inflammatory and antiproliferative effects of delphinidin, a dietary anthocyanidin, in a full-thickness three-dimensional reconstituted human skin model of psoriasis.

Chamcheu JC, Pal HC, Siddiqui IA, Adhami VM, Ayehunie S, Boylan BT, Noubissi FK, Khan N, Syed DN, Elmets CA, Wood GS, Afaq F, Mukhtar H.

Skin Pharmacol Physiol. 2015;28(4):177-88. doi: 10.1159/000368445. Epub 2015 Jan 22.


Topical application of delphinidin reduces psoriasiform lesions in the flaky skin mouse model by inducing epidermal differentiation and inhibiting inflammation.

Pal HC, Chamcheu JC, Adhami VM, Wood GS, Elmets CA, Mukhtar H, Afaq F.

Br J Dermatol. 2015 Feb;172(2):354-64. doi: 10.1111/bjd.13513. Epub 2014 Dec 23.


Role of epithelial mesenchymal transition in prostate tumorigenesis.

Khan MI, Hamid A, Adhami VM, Lall RK, Mukhtar H.

Curr Pharm Des. 2015;21(10):1240-8. Review.

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