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Items: 1 to 20 of 66

1.

Detection and characterization of olmutinib reactive metabolites by LC-MS/MS: Elucidation of bioactivation pathways.

Attwa MW, Kadi AA, Abdelhameed AS.

J Sep Sci. 2019 Nov 18. doi: 10.1002/jssc.201900818. [Epub ahead of print]

PMID:
31788977
2.

Synthesis and antileishmanial evaluation of thiazole orange analogs.

Abdelhameed A, Liao X, McElroy CA, Joice AC, Rakotondraibe L, Li J, Slebodnick C, Guo P, Wilson WD, Werbovetz KA.

Bioorg Med Chem Lett. 2020 Jan 1;30(1):126725. doi: 10.1016/j.bmcl.2019.126725. Epub 2019 Oct 4.

PMID:
31732409
3.

Geant4-based electromagnetic background model for the CRESST dark matter experiment.

Abdelhameed AH, Angloher G, Bauer P, Bento A, Bertoldo E, Breier R, Bucci C, Canonica L, D'Addabbo A, Lorenzo SD, Erb A, Feilitzsch FV, Iachellini NF, Fichtinger S, Fuss A, Gorla P, Hauff D, Jes Kovský M, Jochum J, Kaizer J, Kinast A, Kluck H, Kraus H, Langenkämper A, Mancuso M, Mokina V, Mondragón E, Olmi M, Ortmann T, Pagliarone C, Palus Ová V, Pattavina L, Petricca F, Potzel W, Povinec P, Pröbst F, Reindl F, Rothe J, Schäffner K, Schieck J, Schipperges V, Schmiedmayer D, Schönert S, Schwertner C, Stahlberg M, Stodolsky L, Strandhagen C, Strauss R, Türkoğlu C, Usherov I, Willers M, Zema V, Zeman J.

Eur Phys J C Part Fields. 2019;79(10):881. doi: 10.1140/epjc/s10052-019-7385-0. Epub 2019 Oct 26.

4.

Antiproliferative activity and possible mechanism of action of certain 5-methoxyindole tethered C-5 functionalized isatins.

Almutairi MS, Hassan ES, Keeton AB, Piazza GA, Abdelhameed AS, Attia MI.

Drug Des Devel Ther. 2019 Aug 27;13:3069-3078. doi: 10.2147/DDDT.S208241. eCollection 2019.

5.

Liquid chromatography-tandem mass spectrometry metabolic profiling of nazartinib reveals the formation of unexpected reactive metabolites.

Abdelhameed AS, Attwa MW, Kadi AA.

R Soc Open Sci. 2019 Aug 14;6(8):190852. doi: 10.1098/rsos.190852. eCollection 2019 Aug.

6.

Neutrophil and monocyte receptor expression in patients with sepsis: implications for diagnosis and prognosis of sepsis.

Hanna MOF, Abdelhameed AM, Abou-Elalla AA, Hassan RM, Kostandi I.

Pathog Dis. 2019 Aug 1;77(6). pii: ftz055. doi: 10.1093/femspd/ftz055.

PMID:
31584643
7.

A highly sensitive LC-MS/MS method to determine novel Bruton's tyrosine kinase inhibitor spebrutinib: application to metabolic stability evaluation.

Abdelhameed AS, Attwa MW, Al-Shaklia NS, Kadi AA.

R Soc Open Sci. 2019 Jun 5;6(6):190434. doi: 10.1098/rsos.190434. eCollection 2019 Jun.

8.

Aflibercept with adjuvant micropulsed yellow laser versus aflibercept monotherapy in diabetic macular edema.

Khattab AM, Hagras SM, AbdElhamid A, Torky MA, Awad EA, Abdelhameed AG.

Graefes Arch Clin Exp Ophthalmol. 2019 Jul;257(7):1373-1380. doi: 10.1007/s00417-019-04355-6. Epub 2019 May 24.

PMID:
31127381
9.

Validated LC-MS/MS assay for quantification of the newly approved tyrosine kinase inhibitor, dacomitinib, and application to investigating its metabolic stability.

Abdelhameed AS, Kadi AA, Attwa MW, AlRabiah H.

PLoS One. 2019 Apr 4;14(4):e0214598. doi: 10.1371/journal.pone.0214598. eCollection 2019.

10.

Novel BTK inhibitor acalabrutinib (ACP-196) tightly binds to site I of the human serum albumin as observed by spectroscopic and computational studies.

Abdelhameed AS, Alanazi AM, Bakheit AH, Hassan ES, Herqash RN, Almutairi FM.

Int J Biol Macromol. 2019 Apr 15;127:536-543. doi: 10.1016/j.ijbiomac.2019.01.083. Epub 2019 Jan 18.

PMID:
30664965
11.

Evaluation of the Effect of Combined Low Energy Laser Application and Micro-Osteoperforations versus the Effect of Application of Each Technique Separately On the Rate of Orthodontic Tooth Movement.

Abdelhameed AN, Refai WMM.

Open Access Maced J Med Sci. 2018 Nov 15;6(11):2180-2185. doi: 10.3889/oamjms.2018.386. eCollection 2018 Nov 25.

12.

Reactive intermediates and bioactivation pathways characterization of avitinib by LC-MS/MS: In vitro metabolic investigation.

Attwa MW, Kadi AA, Abdelhameed AS.

J Pharm Biomed Anal. 2019 Feb 5;164:659-667. doi: 10.1016/j.jpba.2018.11.033. Epub 2018 Nov 17.

PMID:
30472584
13.

A Novel Alkaliphilic Streptomyces Inhibits ESKAPE Pathogens.

Terra L, Dyson PJ, Hitchings MD, Thomas L, Abdelhameed A, Banat IM, Gazze SA, Vujaklija D, Facey PD, Francis LW, Quinn GA.

Front Microbiol. 2018 Oct 16;9:2458. doi: 10.3389/fmicb.2018.02458. eCollection 2018.

14.

Practice patterns and outcomes after stroke across countries at different economic levels (INTERSTROKE): an international observational study.

Langhorne P, O'Donnell MJ, Chin SL, Zhang H, Xavier D, Avezum A, Mathur N, Turner M, MacLeod MJ, Lopez-Jaramillo P, Damasceno A, Hankey GJ, Dans AL, Elsayed A, Mondo C, Wasay M, Czlonkowska A, Weimar C, Yusufali AH, Hussain FA, Lisheng L, Diener HC, Ryglewicz D, Pogosova N, Iqbal R, Diaz R, Yusoff K, Oguz A, Wang X, Penaherrera E, Lanas F, Ogah OS, Ogunniyi A, Iversen HK, Malaga G, Rumboldt Z, Magazi D, Nilanont Y, Rosengren A, Oveisgharan S, Yusuf S; INTERSTROKE collaborators.

Lancet. 2018 May 19;391(10134):2019-2027. doi: 10.1016/S0140-6736(18)30802-X. Epub 2018 May 17.

PMID:
29864018
16.

Interaction of catecholamine precursor l-Dopa with lysozyme: A biophysical insight.

Nusrat S, Masroor A, Zaman M, Siddiqi MK, Ajmal MR, Zaidi N, Abdelhameed AS, Khan RH.

Int J Biol Macromol. 2018 Apr 1;109:1132-1139. doi: 10.1016/j.ijbiomac.2017.11.107. Epub 2017 Nov 20.

PMID:
29157902
17.

Biophysical and In Silico Studies of the Interaction between the Anti-Viral Agents Acyclovir and Penciclovir, and Human Serum Albumin.

Abdelhameed AS, Bakheit AH, Almutairi FM, AlRabiah H, Kadi AA.

Molecules. 2017 Nov 5;22(11). pii: E1906. doi: 10.3390/molecules22111906.

18.

Investigating the site selective binding of busulfan to human serum albumin: Biophysical and molecular docking approaches.

Siddiqi M, Nusrat S, Alam P, Malik S, Chaturvedi SK, Ajmal MR, Abdelhameed AS, Khan RH.

Int J Biol Macromol. 2018 Feb;107(Pt B):1414-1421. doi: 10.1016/j.ijbiomac.2017.10.006. Epub 2017 Oct 5.

PMID:
28987797
19.

Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling.

Abdel-Aziz HA, Eldehna WM, Keeton AB, Piazza GA, Kadi AA, Attwa MW, Abdelhameed AS, Attia MI.

Drug Des Devel Ther. 2017 Aug 9;11:2333-2346. doi: 10.2147/DDDT.S140164. eCollection 2017.

20.

Deciphering the enhanced inhibitory, disaggregating and cytoprotective potential of promethazine towards amyloid fibrillation.

Nusrat S, Zaman M, Masroor A, Siddqi MK, Zaidi N, Neelofar K, Abdelhameed AS, Khan RH.

Int J Biol Macromol. 2018 Jan;106:851-863. doi: 10.1016/j.ijbiomac.2017.08.081. Epub 2017 Aug 16.

PMID:
28823512

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