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Nutr Hosp. 2015 Nov 1;32(5):2319-30. doi: 10.3305/nh.2015.32.5.9650.

[ASSOCIATION BETWEEN DIETARY GLYCEMIC INDEX AND GLYCEMIC LOAD AND INTIMA MEDIA THICKNESS IN A POPULATION AT HIGH CARDIOVASCULAR RISK: A SUBGROUP ANALYSIS IN THE PREDIMED TRIAL].

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

1
Atención Primaria, Servicio Navarro de Salud, Osasunbidea, Pamplona. Departamento de Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad de Navarra.. nuria_goni@yahoo.es.
2
Departamento de Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad de Navarra. IdiSNA. Instituto de Investigación Sanitaria de Navarra. CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid.. mamartinez@unav.es.
3
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid. Unidad de Nutrición Humana, Facultad de Medicina y Ciencias de la Salud, Departamento de Bioquímica y Biotecnología, Universidad Rovira I Virgili, Reus.. jordi.salas@urv.cat.
4
Atención Primaria, Servicio Navarro de Salud, Osasunbidea, Pamplona. IdiSNA. Instituto de Investigación Sanitaria de Navarra. CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid.. pilar.buil.cosiales@cfnavarra.es.
5
Atención Primaria, Servicio Navarro de Salud, Osasunbidea, Pamplona. IdiSNA. Instituto de Investigación Sanitaria de Navarra. CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid.. Javier.diez.espino@cfnavarra.es.
6
Departamento de Neurología, Clínica-Universidad de Navarra, Pamplona.. emartinezv@unav.es.
7
Departamento de Neurología, Clínica-Universidad de Navarra, Pamplona.. pirimia@unav.es.
8
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid. Servicio de Endocrinología y Nutrición, Institutd'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clínic (Barcelona), España.. EROS@clinic.ub.es.
9
Departamento de Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad de Navarra. IdiSNA. Instituto de Investigación Sanitaria de Navarra. CIBER Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid.. etolefo@unav.es.

Abstract

in English, Spanish

BACKGROUND:

increased carotid íntima-media thickness (IMT) is a marker of atherosclerosis and a predictor of future cardiovascular events. Although a beneficial effect of Mediterranean diets, in particular, enhanced with virgin olive oil and nuts, on longitudinal changes in IMT has been reported, the association between carbohydrates and the development of atherosclerosis is still unclear.

OBJECTIVE:

to assess the association between glycemic index (IG) and glycemic load (CG) of the diet and intima media thickness (GIMC) in a population at high cardiovascular risk with no clinical symptoms.

METHODS:

one hundred eighty seven participants of the PREDIMED-NAVARRA center (PREDIMED means in Spanish "PREvención con DIeta MEDiterránea") were randomly selected to undergo baseline and 1-year measurement of GIMC. Dietary information was collected at baseline and yearly using a validated 137-item food frequency questionnaire. Participants were categorized into four groups of energy-adjusted IG and CG intake. Multivariate analysis models (ANCOVA) were used to study the association between dietary IG and CG and GIMC and its changes.

RESULTS:

in our study we found no significant association between IG or CG and GIMC at baseline or after one year.

PMID:
26545694
DOI:
10.3305/nh.2015.32.5.9650
[Indexed for MEDLINE]
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