Format

Send to

Choose Destination
Cancer Genet Cytogenet. 1998 Nov;107(1):43-7.

Alveolar rhabdomyosarcoma in a 68-year-old patient identified by cytogenetic analysis of bone marrow.

Author information

1
Institut für Medizinische Biologie, Medizinische Fakultät, Universität Wien, Vienna, Austria.

Abstract

Pancytopenia and fulminant disseminated intravascular coagulation in a 68-year-old woman suggested an acute hematologic malignancy. However, cytogenetic analysis on a bone marrow sample revealed a near-tetraploid karyotype with an isochromosome 1q and a translocation (2;13) (q35;q14), which was suggestive of an alveolar rhabdomyosarcoma (ARMS). This diagnosis was subsequently confirmed by indirect immunohistochemistry. ARMS has not yet been observed in a patient of this age. Thus, our case underlines the importance of cytogenetics, to establish an a priori unexpected tumor diagnosis.

PMID:
9809033
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center