Aetiology of childhood proptosis

J Paediatr Child Health. 1998 Aug;34(4):374-6. doi: 10.1046/j.1440-1754.1998.00243.x.

Abstract

Objective: To retrospectively analyse causes of childhood proptosis and their investigations and treatment.

Methodology: The records of children under 15 years of age presenting with proptosis to The Children's Hospital, Camperdown, Sydney, were reviewed for the period 1983-93 inclusive.

Results: Fifty-seven cases of proptosis were found. In order of frequency the causes were; orbital cellulitis 22, thyroid eye disease 8, optic nerve +/- optic chiasm glioma 8, orbital rhabdomyosarcoma 7, metastatic neuroblastoma 4, orbital neurofibroma 3, orbital haemangioma 2, metastatic Ewing's sarcoma 2 and orbital dermoid cyst 1. Treatment depended on the cause (antibiotics, antithyroid drugs, chemotherapy, radiotherapy, surgery) and was multidisciplinary.

Conclusions: The most common cause of proptosis in children presenting to The Children's Hospital, Camperdown, Sydney, was infective orbital cellulitis. The most useful initial investigation was an orbital computed tomography scan. Treatment depended on the cause of the proptosis and was multidisciplinary.

MeSH terms

  • Adolescent
  • Age of Onset
  • Cellulitis / complications
  • Child
  • Child, Preschool
  • Dermoid Cyst / complications
  • Diagnosis, Differential
  • Exophthalmos / diagnosis
  • Exophthalmos / etiology*
  • Eye Infections / complications
  • Eye Neoplasms / complications
  • Glioma / complications
  • Humans
  • Infant
  • Neurofibromatoses / complications
  • Optic Nerve Diseases / complications
  • Orbital Neoplasms / complications
  • Orbital Neoplasms / secondary
  • Retrospective Studies
  • Rhabdomyosarcoma / complications
  • Thyroid Diseases / complications