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Mult Scler. 1997 Aug;3(4):248-9.

Treatment of multiple sclerosis with high-dose corticosteroids may prolong the prothrombin time to dangerous levels in patients taking warfarin.

Author information

1
Multiple Sclerosis Center, Carolinas Medical Center, Charlotte, North Carolina 28232, USA.

Abstract

Two patients who were taking warfarin experienced significant prolongations of the prothrombin time (protime) after treatment with high-dose corticosteroids for rapid progression of MS. This complication of therapy is potentially life-threatening.

PMID:
9372508
DOI:
10.1177/135245859700300406
[Indexed for MEDLINE]

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