Nasopharyngeal conidiobolomycosis in a horse

J Am Vet Med Assoc. 1996 Jan 1;208(1):100-1.

Abstract

Nasopharyngeal conidiobolomycosis caused by Conidiobolus coronatus was diagnosed in a horse after endoscopic and histopathologic examinations of a biopsy specimen. The fungal lesions in the nasopharynx were substantially reduced in size after intralesional injection of amphotericin B through the biopsy channel of a videoendoscope in combination with i.v. administration of sodium iodide and oral administration of potassium iodide during a 2-month period. Endoscopy performed 15 months after initial examination revealed regression of the granulomatous masses in the nasopharynx and complete disappearance of the nasal masses. Two months later, clinical signs recurred, and the owner elected euthanasia without evaluation and treatment. Nasopharyngeal conidiobolomycosis may be treated successfully with intralesional injection of amphotericin B in combination with administration of sodium iodide and potassium iodide, but there is a possibility of recrudescence of infection.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Amphotericin B / administration & dosage
  • Amphotericin B / therapeutic use*
  • Animals
  • Antifungal Agents / administration & dosage
  • Antifungal Agents / therapeutic use*
  • Endoscopy / veterinary
  • Entomophthora / isolation & purification*
  • Female
  • Granuloma / drug therapy
  • Granuloma / microbiology
  • Granuloma / pathology
  • Granuloma / veterinary
  • Horse Diseases / drug therapy*
  • Horse Diseases / microbiology
  • Horse Diseases / pathology
  • Horses
  • Injections, Intralesional / veterinary
  • Injections, Intravenous / veterinary
  • Mycoses / drug therapy
  • Mycoses / microbiology
  • Mycoses / pathology
  • Mycoses / veterinary*
  • Nasopharyngeal Diseases / drug therapy
  • Nasopharyngeal Diseases / microbiology
  • Nasopharyngeal Diseases / pathology
  • Nasopharyngeal Diseases / veterinary*
  • Potassium Iodide / administration & dosage
  • Potassium Iodide / therapeutic use
  • Recurrence
  • Sodium Iodide / administration & dosage
  • Sodium Iodide / therapeutic use

Substances

  • Antifungal Agents
  • Potassium Iodide
  • Amphotericin B
  • Sodium Iodide