FSH and LH response to LHRF in Kallman's syndrome

M Oettinger; D W Bruneteau; A Psaroudakis; R B Greenblatt

FSH and LH response to LHRF in Kallman's syndrome

Obstet Gynecol. 1976 Feb;47(2):233-6.

Authors

M Oettinger, D W Bruneteau, A Psaroudakis, R B Greenblatt

PMID: 765905

Abstract

The olfacto-genital syndrome (Kallman's syndrome) is believed to be primarily an hypothalamic disorder resulting in hypogonadotropic hypogonadism or hypo-ovarianism and anosmia. The pituitary response in 2 patients was measured on dialy subcutaneous injections of 100 mug of LHRF. One of the patients was also studied in a similar fashion by administration of LHRF intravenously for 4 consecutive days. A greater response occurred with the subcutaneous route.

Publication types

Case Reports

MeSH terms

Adult
Female
Follicle Stimulating Hormone / blood
Follicle Stimulating Hormone / physiology*
Gonadotropin-Releasing Hormone / administration & dosage
Gonadotropin-Releasing Hormone / pharmacology*
Humans
Hypogonadism / physiopathology*
Injections, Intravenous
Injections, Subcutaneous
Luteinizing Hormone / blood
Luteinizing Hormone / physiology*
Male
Olfaction Disorders / physiopathology*
Pituitary Gland / physiopathology
Syndrome

Substances

Gonadotropin-Releasing Hormone
Luteinizing Hormone
Follicle Stimulating Hormone