The term "exogenic pneumopathology" means a cluster of problems resulting from the still unknown consequences of the exposure of workmen to various industrial noxious agents. Progress is to be expected from advanced methods of examination: Perbronchial lung biopsy is a new chance to solve the problems. With perbronchial biopsy we get lung tissue in about 90% of examined cases. The complication rates are low: pneumothorax developed in about 4% controllable bleedings occurred in 1.2%. Relevant diagnostic results were possible in about 60%. From the tabulated global results after more than 1400 perbronchial lung biopsies, the occupational diseases and the lung fibrosis are especially pointed out and discussed in detail.