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An Overview of the Randomized Placebo-Controlled Trials of Chinese Herbal Medicine Formula Granules.
Han M, Lai L, Li XX, Zhao NQ, Li J, Xia Y, Liu JP. Han M, et al. Evid Based Complement Alternat Med. 2019 Apr 11;2019:6486293. doi: 10.1155/2019/6486293. eCollection 2019. Evid Based Complement Alternat Med. 2019. PMID: 31110552 Free PMC article. Review.
And, the heat-clearing and detoxifying formula granules were superior to placebo in resolution of cold symptom among patients with fever with a RR and 95% CI of 2.58 [1.40,4.74]. ...However, both the absolute and relative effectiveness of CHM formula granules compar …
And, the heat-clearing and detoxifying formula granules were superior to placebo in resolution of cold symptom among patients with fe …
Prediction of risk of prolonged post-concussion symptoms: Derivation and validation of the TRICORDRR (Toronto Rehabilitation Institute Concussion Outcome Determination and Rehab Recommendations) score.
Langer LK, Alavinia SM, Lawrence DW, Munce SEP, Kam A, Tam A, Ruttan L, Comper P, Bayley MT. Langer LK, et al. PLoS Med. 2021 Jul 8;18(7):e1003652. doi: 10.1371/journal.pmed.1003652. eCollection 2021 Jul. PLoS Med. 2021. PMID: 34237056 Free PMC article.
Total cohort was divided into Derivation (2009 to 2013, n = 417,335) and Validation cohorts (2009 and 2014, n = 169,722) based upon injury index year. Variables selected a priori such as psychiatric disorders, migraines, sleep disorders, demographic fa …
Total cohort was divided into Derivation (2009 to 2013, n = 417,335) and Validation cohorts (2009 and 2014, n = 169,722) based upon injury i …
Use of ergotamine: do physicians in Colombia know how to prescribe it?
Machado-Alba JE, Morales-Plaza CD. Machado-Alba JE, et al. Neurologia. 2014 Jun;29(5):280-5. doi: 10.1016/j.nrl.2013.06.009. Epub 2013 Sep 10. Neurologia. 2014. PMID: 24035295 Free article. English, Spanish.
METHODS: We reviewed 86 411 formulas during April 2012, identifying the prescription by drug, dose, interval, duration of use, and indication. We interviewed 288 randomly selected patients in whom we also investigated concomitant use of a) antihypertensive agents b) …
METHODS: We reviewed 86 411 formulas during April 2012, identifying the prescription by drug, dose, interval, duration of use, and in …
Coated Lipidic Nanoparticles as a New Strategy for Enhancing Nose-to-Brain Delivery of a Hydrophilic Drug Molecule.
Salem LH, El-Feky GS, Fahmy RH, El Gazayerly ON, Abdelbary A. Salem LH, et al. J Pharm Sci. 2020 Jul;109(7):2237-2251. doi: 10.1016/j.xphs.2020.04.007. Epub 2020 Apr 19. J Pharm Sci. 2020. PMID: 32320670
Oral Almotriptan maleate (ALM) is used in the treatment of migraine; however, due to its extreme aqueous solubility, shows poor penetration and lesser concentration in the brain thus requiring frequent oral dosing. ...The prepared systems were then assessed for their parti …
Oral Almotriptan maleate (ALM) is used in the treatment of migraine; however, due to its extreme aqueous solubility, shows poor penet …
The in vivo pharmacological profile of a 5-HT1 receptor agonist, CP-122,288, a selective inhibitor of neurogenic inflammation.
Gupta P, Brown D, Butler P, Ellis P, Grayson KL, Land GC, Macor JE, Robson SF, Wythes MJ, Shepperson NB. Gupta P, et al. Br J Pharmacol. 1995 Nov;116(5):2385-90. doi: 10.1111/j.1476-5381.1995.tb15084.x. Br J Pharmacol. 1995. PMID: 8581273 Free PMC article.
Interestingly, doses of CP-122,288 that inhibit neurogenic inflammation in rat dura mater (0.3-300 ng kg-1) were demonstrated to be devoid of vasoconstrictor activity in either the carotid or coronary vascular beds of dog. 7. These data demonstrate that in the rat, CP-122, …
Interestingly, doses of CP-122,288 that inhibit neurogenic inflammation in rat dura mater (0.3-300 ng kg-1) were demonstrated to be devoid o …