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Mol Biol Evol. 1984 Sep;1(5):411-22.

Bacterial transposon Tn5: evolutionary inferences.

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Department of Microbiology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63110.


Transposable elements induce spontaneous mutations, promote genome rearrangements, regulate gene expression, and participate in the horizontal spread of genes encoding traits such as antibiotic resistance among bacterial genera too distantly related to undergo homologous recombination. Here we review the bacterial transposon Tn5 and focus on those aspects of its functional organization and transposition which provide insights into how it and other elements may have arisen, proliferated, and evolved.

[Indexed for MEDLINE]

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