Varicella zoster virus associated-polyradiculoneuritis in an elderly woman: A new subtype of varicella zoster virus neuropathy

Rinsho Shinkeigaku. 2022 Dec 17;62(12):935-939. doi: 10.5692/clinicalneurol.cn-001794. Epub 2022 Nov 29.

Abstract

An 82-year-old Japanese woman without underlying disease was admitted to our hospital 3 days after she noticed lower-limb weakness. At presentation, she had lower-leg motor paralysis with mild upper-limb paresis and left Ramsay Hunt syndrome. Cerebrospinal fluid (CSF) findings revealed moderate pleocytosis. A polymerase chain reaction for varicella zoster virus (VZV) DNA in CSF was positive. MRI using 3D Nerve-VIEW (Philips) and contrast T1 images showed high-intensity lesions on the L2-5 and S1-2 spinal roots. A new subtype of VZV-associated polyradiculoneuritis was diagnosed in this patient. We provide the case details and compare three similar reported cases.

Keywords: Ramsay Hunt syndrome; herpes zoster; meningitis; polyradiculoneuritis; varicella zoster virus.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Female
  • Herpes Zoster Oticus* / diagnosis
  • Herpes Zoster* / diagnosis
  • Herpesvirus 3, Human / genetics
  • Humans
  • Magnetic Resonance Imaging
  • Polymerase Chain Reaction
  • Polyradiculoneuropathy* / diagnosis
  • Polyradiculoneuropathy* / etiology