Management of refractory Acanthamoeba keratitis, two cases

Parasitol Res. 2021 Mar;120(3):1121-1124. doi: 10.1007/s00436-020-06997-6. Epub 2021 Jan 6.

Abstract

Acanthamoeba keratitis is a serious infection of the eye that can result in permanent visual impairment or blindness, caused by free-living amoebae of the genus Acanthamoeba. Early diagnosis is necessary for effective treatment of Acanthamoeba keratitis. Acanthamoeba is abundant in nature and can be found in water, soil, and air. Acanthamoeba keratitis is usually diagnosed by culture from a scraping of the eye or by confocal microscopy. In this paper, two complicated Acanthamoeba keratitis cases are reported.

Keywords: Acanthamoeba keratitis; Diagnosis; In vivo confocal imaging; Penetrating keratoplasty; Treatment.

Publication types

  • Case Reports

MeSH terms

  • Acanthamoeba / isolation & purification
  • Acanthamoeba Keratitis / diagnosis*
  • Acanthamoeba Keratitis / therapy*
  • Adult
  • Female
  • Humans
  • Keratoplasty, Penetrating
  • Microscopy, Confocal
  • Retrospective Studies
  • Treatment Outcome
  • Voriconazole / administration & dosage

Substances

  • Voriconazole