Intraventricular nafcillin-induced seizures in a neonate

Pediatr Neurol. 1988 May-Jun;4(3):188-90. doi: 10.1016/0887-8994(88)90011-2.

Abstract

Treatment of cerebrospinal fluid shunt infections commonly involves a combination of intravenous and intraventricular antibiotics. We report a premature infant who developed seizures associated with intraventricular administration of nafcillin and discuss the need for electroencephalographic monitoring of patients receiving intraventricular antibiotics.

Publication types

  • Case Reports

MeSH terms

  • Abscess / drug therapy*
  • Cerebrospinal Fluid Shunts
  • Humans
  • Hydrocephalus / surgery
  • Infant, Newborn
  • Infant, Premature, Diseases / drug therapy*
  • Injections, Intraventricular
  • Male
  • Nafcillin / administration & dosage
  • Nafcillin / adverse effects*
  • Postoperative Complications / drug therapy
  • Spasms, Infantile / chemically induced*
  • Staphylococcal Infections / drug therapy*

Substances

  • Nafcillin