Schizophyllum commune sphenoidal sinusitis as presentation of a non-Hodgkin Lymphoma

Rita Filipe; João Paulo Caldas; Neuza Soares; Raquel Sabino; Cristina Veríssimo; Roberto Silva; André Silva-Pinto; Margarida Tavares; António Sarmento

doi:10.1016/j.mmcr.2020.04.003

Schizophyllum commune sphenoidal sinusitis as presentation of a non-Hodgkin Lymphoma

Med Mycol Case Rep. 2020 Apr 6:28:26-28. doi: 10.1016/j.mmcr.2020.04.003. eCollection 2020 Jun.

Authors

Rita Filipe^{1

2}, João Paulo Caldas^{1

2}, Neuza Soares³, Raquel Sabino⁴, Cristina Veríssimo⁴, Roberto Silva⁵, André Silva-Pinto^{1

2}, Margarida Tavares^{1

6}, António Sarmento^{1

2}

Affiliations

¹ Infectious Diseases Department, Centro Hospitalar Universitário São João, Alameda Hernâni Monteiro, 4200-319, Porto, Portugal.
² Faculty of Medicine of Porto, Centro Hospitalar Universitário São João, Portugal.
³ Internal Medicine Department, Centro Hospitalar Universitário São João, Portugal.
⁴ Reference Unit for Parasitic and Fungal Infections, Department of Infectious Diseases, National Institute of Health Dr. Ricardo Jorge, 1649-016, Lisbon, Portugal.
⁵ Pathology Department, Centro Hospitalar Universitário São João, Portugal.
⁶ EPI Unit, Public Health Institute of University of Porto, Portugal.

Abstract

Schizophyllum commune is a basidiomycetes worldwide distributed that has emerged as cause of invasive infections in immunosuppressed patients. We present a case of a man who was simultaneously diagnosed with a small cell non-Hodgkin lymphoma and a sphenoid sinusitis by S. commune. Intraoperative observation and histology description were crucial to consider an alternative diagnosis to mucormycosis suggested by the MRI. The diagnosis was made based on PCR identification and sequencing.

Keywords: Fungal sinusitis; Immunosuppression; Non-Hodgkin lymphoma; Schizophyllum commune.

Publication types

Case Reports