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Mil Med Res. 2020 Feb 6;7(1):4. doi: 10.1186/s40779-020-0233-6.

A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version).

Author information

1
Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
2
Institute of Hospital Management, Wuhan University, Wuhan, 430071, China.
3
Department of Respiratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
4
Department of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
5
Institute of Evidence-Based Medicine and Knowledge Translation, Henan University, Kaifeng, 475000, China.
6
China Academy of Chinese Medical Sciences, Beijing, 100700, China.
7
China Center for Evidence Based Traditional Chinese Medicine (CCEBTCM), Beijing, 100700, China.
8
Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
9
Department of Clinical Laboratory, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
10
Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
11
Division of Medical Affairs, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
12
Division of Nursing Affairs, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
13
Office of Nosocomial Infection Control, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
14
Emergency Center, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
15
Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
16
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, L8S 4L8, Canada.
17
Department of Traditional Chinese Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
18
Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. zengxiantao1128@163.com.
19
Global Health Institute, Wuhan University, Wuhan, 430072, China. zengxiantao1128@163.com.
20
China Academy of Chinese Medical Sciences, Beijing, 100700, China. wangyyanpublic@bta.net.cn.
21
China Center for Evidence Based Traditional Chinese Medicine (CCEBTCM), Beijing, 100700, China. wangyyanpublic@bta.net.cn.
22
Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. wangxinghuan1965@163.com.
23
Institute of Hospital Management, Wuhan University, Wuhan, 430071, China. wangxinghuan1965@163.com.

Abstract

In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province; and then named "2019 novel coronavirus (2019-nCoV)" by the World Health Organization (WHO) on 12 January 2020. For it is a never been experienced respiratory disease before and with infection ability widely and quickly, it attracted the world's attention but without treatment and control manual. For the request from frontline clinicians and public health professionals of 2019-nCoV infected pneumonia management, an evidence-based guideline urgently needs to be developed. Therefore, we drafted this guideline according to the rapid advice guidelines methodology and general rules of WHO guideline development; we also added the first-hand management data of Zhongnan Hospital of Wuhan University. This guideline includes the guideline methodology, epidemiological characteristics, disease screening and population prevention, diagnosis, treatment and control (including traditional Chinese Medicine), nosocomial infection prevention and control, and disease nursing of the 2019-nCoV. Moreover, we also provide a whole process of a successful treatment case of the severe 2019-nCoV infected pneumonia and experience and lessons of hospital rescue for 2019-nCoV infections. This rapid advice guideline is suitable for the first frontline doctors and nurses, managers of hospitals and healthcare sections, community residents, public health persons, relevant researchers, and all person who are interested in the 2019-nCoV.

KEYWORDS:

2019 novel coronavirus; 2019-nCoV; Clinical practice guideline; Evidence-based medicine; Infectious diseases; Pneumonia; Rapid advice guideline; Respiratory disease

PMID:
32029004
PMCID:
PMC7003341
DOI:
10.1186/s40779-020-0233-6
[Indexed for MEDLINE]
Free PMC Article

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