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MMWR Morb Mortal Wkly Rep. 2020 Feb 7;69(5):140-146. doi: 10.15585/mmwr.mm6905e1.

Initial Public Health Response and Interim Clinical Guidance for the 2019 Novel Coronavirus Outbreak - United States, December 31, 2019-February 4, 2020.

Collaborators (178)

Abdirizak F2, Abedi G2, Aggarwal S2, Albina D3, Allen E3, Andersen L3, Anderson J4, Anderson M4, Anderson T5, Anderson K6, Bardossy AC3, Barry V7, Beer K3, Bell M3, Berger S8, Bertulfo J8, Biggs H2, Bornemann J8, Bornstein J8, Bower W3, Bresee J2, Brown C3, Budd A2, Buigut J3, Burke S2, Burke R2, Burns E2, Butler J9, Cantrell R5, Cardemil C2, Cates J2, Cetron M3, Chatham-Stephens K6, Chatham-Stevens K6, Chea N3, Christensen B3, Chu V2, Clarke K10, Cleveland A2, Cohen N3, Cohen M5, Cohn A2, Collins J11, Dahl R2, Daley W4, Dasari V5, Davlantes E5, Dawson P3, Delaney L12, Donahue M5, Dowell C12, Dyal J2, Edens W2, Eidex R13, Epstein L3, Evans M7, Fagan R3, Farris K2, Feldstein L2, Fox L2, Frank M4, Freeman B2, Fry A2, Fuller J10, Galang R14, Gerber S2, Gokhale R3, Goldstein S2, Gorman S4, Gregg W2, Greim W3, Grube S8, Hall A2, Haynes A2, Hill S2, Hornsby-Myers J12, Hunter J13, Ionta C2, Isenhour C2, Jacobs M5, Slifka KJ3, Jernigan D2, Jhung M3, Jones-Wormley J4, Kambhampati A2, Kamili S2, Kennedy P2, Kent C15, Killerby M2, Kim L2, Kirking H2, Koonin L2, Koppaka R2, Kosmos C4, Kuhar D3, Kuhnert-Tallman W16, Kujawski S2, Kumar A17, Landon A8, Lee L2, Leung J2, Lindstrom S2, Link-Gelles R2, Lively J2, Lu X2, Lynch B2, Malapati L2, Mandel S2, Manns B2, Marano N3, Marlow M2, Marston B10, McClung N2, McClure L10, McDonald E3, McGovern O2, Messonnier N2, Midgley C2, Moulia D2, Murray J2, Noelte K4, Noonan-Smith M8, Nordlund K2, Norton E12, Oliver S2, Pallansch M2, Parashar U2, Patel A2, Patel M2, Pettrone K18, Pierce T3, Pietz H4, Pillai S3, Radonovich L12, Reagan-Steiner S3, Reel A2, Reese H2, Rha B2, Ricks P10, Rolfes M2, Roohi S3, Roper L2, Rotz L3, Routh J2, Sakthivel SK2, Sarmiento L12, Schindelar J3, Schneider E2, Schuchat A8, Scott S5, Shetty V5, Shockey C3, Shugart J12, Stenger M19, Stuckey M3, Sunshine B3, Sykes T8, Trapp J8, Uyeki T2, Vahey G3, Valderrama A3, Villanueva J3, Walker T4, Wallace M2, Wang L2, Watson J2, Weber A12, Weinbaum C2, Weldon W2, Westnedge C2, Whitaker B2, Whitaker M2, Williams A8, Williams H8, Willams I3, Wong K15, Xie A5, Yousef A2.

Author information

Incident Manager, 2019-nCoV CDC Response, CDC.
National Center for Immunization and Respiratory Diseases, CDC.
National Center for Emerging and Zoonotic Infectious Diseases, CDC.
Center for Preparedness and Response, CDC.
Center for State, Tribal, Local and Territorial Support, CDC.
National Center on Birth Defects and Developmental Disabilities, CDC.
National Center for Injury Prevention and Control, CDC.
Office of the Director, CDC.
Office of the Deputy Director of Infectious Disease, CDC.
Center for Global Health, CDC.
National Center for Emerging and Zoonotic Infectious Diseases, CDC; Erin Conners, National Center for Emerging and Zoonotic Infectious Diseases, CDC; Aaron Curns, National Center for Immunization and Respiratory Diseases, CDC.
National Institute for Occupational Safety and Health, CDC.
, National Center for Emerging and Zoonotic Infectious Diseases, CDC.
National Center for Chronic Disease Prevention and Promotion, CDC.
Center for Surveillance, Epidemiology and Laboratory Services, CDC.
Deputy Director for Infectious Diseases, CDC.
, National Center for Immunization and Respiratory Diseases, CDC.
National Center for Health Statistics, CDC.
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC.

Erratum in


On December 31, 2019, Chinese health officials reported a cluster of cases of acute respiratory illness in persons associated with the Hunan seafood and animal market in the city of Wuhan, Hubei Province, in central China. On January 7, 2020, Chinese health officials confirmed that a novel coronavirus (2019-nCoV) was associated with this initial cluster (1). As of February 4, 2020, a total of 20,471 confirmed cases, including 2,788 (13.6%) with severe illness,* and 425 deaths (2.1%) had been reported by the National Health Commission of China (2). Cases have also been reported in 26 locations outside of mainland China, including documentation of some person-to-person transmission and one death (2). As of February 4, 11 cases had been reported in the United States. On January 30, the World Health Organization (WHO) Director-General declared that the 2019-nCoV outbreak constitutes a Public Health Emergency of International Concern. On January 31, the U.S. Department of Health and Human Services (HHS) Secretary declared a U.S. public health emergency to respond to 2019-nCoV.§ Also on January 31, the president of the United States signed a "Proclamation on Suspension of Entry as Immigrants and Nonimmigrants of Persons who Pose a Risk of Transmitting 2019 Novel Coronavirus," which limits entry into the United States of persons who traveled to mainland China to U.S. citizens and lawful permanent residents and their families (3). CDC, multiple other federal agencies, state and local health departments, and other partners are implementing aggressive measures to slow transmission of 2019-nCoV in the United States (4,5). These measures require the identification of cases and their contacts in the United States and the appropriate assessment and care of travelers arriving from mainland China to the United States. These measures are being implemented in anticipation of additional 2019-nCoV cases in the United States. Although these measures might not prevent the eventual establishment of ongoing, widespread transmission of the virus in the United States, they are being implemented to 1) slow the spread of illness; 2) provide time to better prepare health care systems and the general public to be ready if widespread transmission with substantial associated illness occurs; and 3) better characterize 2019-nCoV infection to guide public health recommendations and the development of medical countermeasures including diagnostics, therapeutics, and vaccines. Public health authorities are monitoring the situation closely. As more is learned about this novel virus and this outbreak, CDC will rapidly incorporate new knowledge into guidance for action by CDC and state and local health departments.

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