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Nucleic Acids Res. 2019 Nov 16. pii: gkz948. doi: 10.1093/nar/gkz948. [Epub ahead of print]

ParameciumDB 2019: integrating genomic data across the genus for functional and evolutionary biology.

Author information

1
I2BC, Institute of Integrative Biology of the Cell, UMR9198, CNRS, CEA, Univ Paris-Sud, Université Paris-Saclay, 91198 Gif-sur-Yvette, France.
2
IBENS, Département de Biologie, Ecole Normale Supérieure, CNRS, Inserm, PSL Research University, F-75005 Paris, France.

Abstract

ParameciumDB (https://paramecium.i2bc.paris-saclay.fr) is a community model organism database for the genome and genetics of the ciliate Paramecium. ParameciumDB development relies on the GMOD (www.gmod.org) toolkit. The ParameciumDB web site has been publicly available since 2006 when the P. tetraurelia somatic genome sequence was released, revealing that a series of whole genome duplications punctuated the evolutionary history of the species. The genome is linked to available genetic data and stocks. ParameciumDB has undergone major changes in its content and website since the last update published in 2011. Genomes from multiple Paramecium species, especially from the P. aurelia complex, are now included in ParameciumDB. A new modern web interface accompanies this transition to a database for the whole Paramecium genus. Gene pages have been enriched with orthology relationships, among the Paramecium species and with a panel of model organisms across the eukaryotic tree. This update also presents expert curation of Paramecium mitochondrial genomes.

PMID:
31733062
DOI:
10.1093/nar/gkz948

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