Oral leukoplakia; a proposal for simplification and consistency of the clinical classification and terminology

Med Oral Patol Oral Cir Bucal. 2019 Nov 1;24(6):e799-e803. doi: 10.4317/medoral.23372.

Abstract

There is a distinct lack of uniformity in the definitions and clinical terminologies related to oral leukoplakia and leukoplakialike lesions and disorders. Proposals have been put forward to subclassify leukoplakia into a homogeneous and a non-homogeneous type based on color only, being either predominantly white or mixed whiteand-red, respectively, irrespective of the texture of the lesion. In this proposal there is no need anymore to regard the poorly defined proliferative verrucous leukoplakia as a separate entity. Since keratosis is primarily a histopathological term, its clinical use is discouraged. Alternative terminology for these so-called keratotic lesions and disorders has been put forward. Finally, a suggestion has been made to rename the term hairy leukoplakia, being a well defined, not potentially malignant disorder particularly related to HIV-infection, into 'EBV-positive white lesion of the tongue (EBVposWLT).

MeSH terms

  • HIV Infections*
  • Humans
  • Leukoplakia, Oral
  • Tongue
  • Tongue Diseases*