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Front Biosci (Schol Ed). 2020 Jan 1;12:57-69.

Prevention of atherosclerosis: the role of special diets and functional foods.

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Plekhanov Russian University of Economics, Stremyanny Pereulok 36, 117997 Moscow, Russia,
Institute of Human Morphology, Tsyurupa str. 3, 117418, Moscow, Russia.
Institute of General Pathology and Pathophysiology, Moscow, Russia.
Institute of Cellular and System Medicine, National Health Research Institutes, 35 Keyan Road, Zhunan Town, Miaoli County 35053, Taiwan R.O.C.
Laboratory of Medical Genetics, National Medical Research Center of Cardiology, 15A 3-rd Cherepkovskaya Street, Moscow 121552, Russia.


The importance of diet for prevention of atherosclerosis is supported by numerous studies. However, to date, no rigorous method exists to assess its impact. Dietary ingredients and supplements and functional foods receive special attention as promising components in prevention of atherosclerosis. In this review, we summarize the results of recent studies that demonstrate the direct and indirect effects of functional foods and dietary components on the initiation and progression of atherosclerosis. We discuss the possible effects of different diets on the pathological mechanisms at cellular and molecular level, as well as epidemiological and clinical observations.


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