Clinical Features and Histopathology of Cardiac Sarcoidosis with Refractory Heart Failure: An Autopsy Case

Intern Med. 2019 Dec 15;58(24):3551-3555. doi: 10.2169/internalmedicine.3147-19. Epub 2019 Aug 21.

Abstract

Treatment involving the insertion of an implantable cardioverter defibrillator and cardiac resynchronization therapy devices has markedly improved the prognosis of cardiac sarcoidosis. However, the prognosis remains poor in patients with advanced cardiac dysfunction or heart failure. We herein report the clinical course and histopathological findings of the autopsied heart of a patient with cardiac sarcoidosis with long-term refractory heart failure.

Keywords: dilated cardiomyopathy; heart failure; pathology; prognosis; sarcoidosis.

Publication types

  • Case Reports

MeSH terms

  • Atrioventricular Block / therapy*
  • Autopsy
  • Cardiac Resynchronization Therapy Devices
  • Cardiac Resynchronization Therapy*
  • Cardiomyopathies / complications
  • Cardiomyopathies / pathology*
  • Cardiomyopathies / therapy
  • Defibrillators, Implantable
  • Echocardiography
  • Electrocardiography
  • Fatal Outcome
  • Heart Failure / diagnostic imaging
  • Heart Failure / etiology
  • Heart Failure / pathology*
  • Humans
  • Lung / pathology
  • Male
  • Middle Aged
  • Myocardium / pathology*
  • Sarcoidosis / complications
  • Sarcoidosis / pathology*