Management of atherogenic dyslipidemia in the primary care setting in Spain

Clin Investig Arterioscler. 2019 Sep-Oct;31(5):203-209. doi: 10.1016/j.arteri.2019.03.001. Epub 2019 Jul 15.
[Article in English, Spanish]

Abstract

Aim: To describe the management of atherogenic dyslipidemia (AD) in routine clinical practice in the Primary Care (PC) setting in Spain.

Methods: Observational, descriptive, cross-sectional study based on a structured questionnaire designed for this study and addressed to PC physicians. The questionnaire content was based on a literature review and was validated by 3 experts in AD.

Results: A total of 1029 PC physicians participated in the study. 96.99% indicated that AD is determinant for cardiovascular risk, even if LDL-C levels are appropriate. 88.43% evaluated residual cardiovascular risk in their clinical practice, however, only 27.89% of them evaluated it in secondary prevention. Regarding diagnosis, 82.22% reported that TC, TG, HDL-C and non-HDL-C are essential measures when evaluating AD. Almost all physicians reported that they can request fractionated cholesterol to assess HDL-C and LDL-C, however 3.69% could not. Physicians (95.63%) considered that the first step in AD treatment should be diet, regular exercise, smoking cessation and pharmaceutical treatment, if necessary. 19.1% agreed partially or completely that gemfibrozil is the most suitable fibrate to associate with statins. 74.83% completely agreed that fenofibrate is the most suitable fibrate to combine with statins.

Conclusions: Physicians have access to general Spanish guidelines and recommendations associated with AD management, however, it is necessary to continue rising awareness about the importance of early detection and optimal control of AD to reduce patients' cardiovascular risk.

Keywords: Atención primaria; Atherogenic dyslipidemia; Cardiovascular risk; Dislipemia aterogénica; Primary care; Riesgo cardiovascular.

Publication types

  • Observational Study

MeSH terms

  • Atherosclerosis / diagnosis
  • Atherosclerosis / therapy*
  • Cross-Sectional Studies
  • Dyslipidemias / diagnosis
  • Dyslipidemias / therapy*
  • Female
  • Fenofibrate / administration & dosage
  • Gemfibrozil / administration & dosage
  • Health Care Surveys
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage
  • Hypolipidemic Agents / administration & dosage
  • Lipids / blood
  • Male
  • Middle Aged
  • Physicians, Primary Care / statistics & numerical data*
  • Primary Health Care / methods*
  • Primary Health Care / statistics & numerical data
  • Spain

Substances

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Hypolipidemic Agents
  • Lipids
  • Gemfibrozil
  • Fenofibrate