Format

Send to

Choose Destination
Ann Neurol. 2019 Sep;86(3):452-457. doi: 10.1002/ana.25551. Epub 2019 Jul 31.

High-resolution diffusion-weighted imaging identifies ischemic lesions in a majority of transient ischemic attack patients.

Author information

1
Center for Stroke Research Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany.
2
Klinik und Hochschulambulanz für Neurologie, Charité Universitätsmedizin Berlin, Berlin, Germany.
3
Berlin Institute of Health, Berlin, Germany.
4
Department of Neurology, Jewish Hospital, Berlin, Germany.
5
Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
6
German Centre for Cardiovascular Research (DZHK), Berlin, Germany.
7
German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.

Abstract

Transient ischemic attack (TIA) is defined as focal neurological deficit caused by ischemia resolving within 24 hours. In a secondary analysis of a large monocentric cohort of 446 TIA patients, we explored the frequency and determinants of diffusion-weighted imaging (DWI) lesions on high-resolution magnetic resonance imaging. Overall, 240 (54%) of all TIA patients presented with DWI lesions. These patients had higher National Institute of Health Stroke Scale and ABCD2 scores and presented more frequently with vessel occlusion and perfusion deficits, but had similar functional outcome at 3 months. Taken together, high-resolution DWI provides evidence of ischemic brain injury in the majority of TIA patients. ANN NEUROL 2019;86:452-457.

PMID:
31298762
DOI:
10.1002/ana.25551

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center