Effects of psychosocial stress on the hormonal and affective response in children with dyslexia

Trends Neurosci Educ. 2019 Jun:15:1-9. doi: 10.1016/j.tine.2019.03.001. Epub 2019 Mar 8.

Abstract

Introduction: Research on stress and dyslexia has mainly focused on chronic and contextual stress caused by the school environment. Our goal was to test individual differences in the hypothalamic-pituitary-adrenal (HPA) axis reactivity of dyslexic and non-dyslexic children and the related emotional manifestations associated with exposure to a psychosocial stressor.

Methods: Eighty-one children (11-14 years old; 38 dyslexic) were exposed to the Trier Social Stress Test adapted to children or to a control condition. The salivary cortisol response, anxiety, and mood were measured before and after the stress.

Results: Dyslexic children did not show the expected cortisol response, as the highest percentage of children who were non-reactive to stress was found in this group. Cortisol reactivity to stress was related to higher levels of anxiety and lower positive affect in the non-dyslexic children.

Conclusion: These results suggest a pattern of hypo-activation of the HPA axis to psychosocial stress in children with dyslexia.

Keywords: Dyslexia; Hormonal response, Mood; Psychosocial stress.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Dyslexia / metabolism*
  • Dyslexia / psychology*
  • Female
  • Humans
  • Hydrocortisone / analysis
  • Hydrocortisone / metabolism
  • Hypothalamo-Hypophyseal System / physiology*
  • Male
  • Stress, Psychological / metabolism*
  • Stress, Psychological / psychology

Substances

  • Hydrocortisone