Format

Send to

Choose Destination
Med Sci (Paris). 2019 Mar;35(3):232-235. doi: 10.1051/medsci/2019037. Epub 2019 Apr 1.

[Pathological consequences of excess of interferon in vivo].

[Article in French]

Author information

1
Faculté de médecine Paris Descartes, 15, rue de l'École de médecine, 75006 Paris, France.
2
Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Royaume-Uni - Laboratory of Neurogenetics and Neuroinflammation, Institute Imagine, Paris, France.
3
St. Giles Lab of Human Genetics of Infectious Diseases, The Rockefeller University, New York, USA Howard Hughes Medical Institute, New York, États-Unis - Lab of Human Genetics of Infectious Diseases, Inserm UMR 1163, Necker Hospital for Sick Children, Paris, France Paris Descartes University, Imagine Institute, Paris, France - Pediatric Hematology and Immunology Unit, Necker Hospital for Sick Children, Paris, France.
4
CNRS, Paris, France.

Abstract

In this brief review, the authors present a history of the different aspects of the scientific puzzle leading from pioneer animal studies and astute clinical experimental observations to a mature appreciation of the deleterious role of excess of a type I interferon in human pathology.

PMID:
30931907
DOI:
10.1051/medsci/2019037

Supplemental Content

Full text links

Icon for EDP Sciences
Loading ...
Support Center