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Open Access Maced J Med Sci. 2019 Feb 15;7(4):617-622. doi: 10.3889/oamjms.2019.044. eCollection 2019 Feb 28.

Correlation of ABO Blood Groups and Rh Factor with The Severity of Generalized Chronic Periodontitis: Across Sectional Study in Riyadh, Saudi Arabia.

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Department of Preventive Dental Sciences, Al Farabi Colleges, Riyadh, KSA.
Department of Preventive Dental Sciences, College of Dentistry, Dar Al Uloom University, Riyadh, KSA.
Department of Basic Sciences, Al Farabi Colleges, Riyadh, KSA.



The development of periodontal diseases depends on the presence of causative microorganisms, host immunity and risk factors. Although variability present among the types of periodontal diseases, all are represented to a shared interaction between host and bacteria. ABO blood groups are the most investigated erythrocyte antigen system. However, limited investigations have been conducted to explore the alliance between ABO blood groups and periodontal diseases.


Our purpose was to explore any possible association between the severity of chronic periodontitis with ABO blood groups and Rh factor.


A cross-sectional study was carried out on 205 patients out of 1126 generalised chronic periodontitis patients (GCP) who were referred to Al-Farabi Colleges, Riyadh, Saudi Arabia. They were categorized into; group I (mild), group II (moderate) and group III (sever).


The patients with blood group O were at a greater risk to develop GCP irrespective of its severity, followed by those with blood group A, B, and AB. The dispensation of the Rh factor in all groups exhibited a significantly greater distribution of Rh positive.


Genetic factors such as ABO blood group antigens may act as a risk influencer that affects the progression and severity of the chronic periodontitis.


ABO Blood Groups; Chronic periodontitis; Periodontal Diseases; Rh Factor; Severity

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