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Clin Nucl Med. 2019 May;44(5):412-413. doi: 10.1097/RLU.0000000000002513.

68Ga-DOTATOC PET/CT Differentiates Meningioma From Dural Metastases.

Author information

1
Departments of Neuropathology.
2
Radiology.
3
Radiation Oncology, and.

Abstract

A 77-year-old woman with history of breast cancer presented with 2 unclear dural contrast-enhancing lesions on MRI; differential diagnoses were breast cancer metastases and meningiomas. On Ga-DOTATOC PET/CT, the temporal lesion showed high uptake and was classified as meningioma, whereas the lesion at the falx showed barely any Ga-DOTATOC uptake uncharacteristic for meningioma and suggestive for a brain metastasis. After resection, histological specimens from the temporal lesion showed meningioma tissue with distinct SSTR2A expression, whereas the falx lesion revealed a breast cancer metastasis without significant SSTR2A expression. Therefore, Ga-DOTATOC PET represents a powerful imaging modality for the evaluation of unclear dural lesions.

PMID:
30829858
DOI:
10.1097/RLU.0000000000002513
[Indexed for MEDLINE]

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