Format

Send to

Choose Destination
Bioinformatics. 2019 Mar 1;35(5):886-888. doi: 10.1093/bioinformatics/bty737.

QuantiNemo 2: a Swiss knife to simulate complex demographic and genetic scenarios, forward and backward in time.

Author information

1
Vital-IT, Swiss Institute of Bioinformatics, Lausanne, Switzerland.
2
Department of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland.
3
Swiss Institute of Bioinformatics, Lausanne, Switzerland.

Abstract

SUMMARY:

QuantiNemo 2 is a stochastic simulation program for quantitative population genetics. It was developed to investigate the effects of selection, mutation, recombination and drift on quantitative traits and neutral markers in structured populations connected by migration and located in heterogeneous habitats. A specific feature is that it allows to switch between an individual-based full-featured mode and a population-based faster mode. Several demographic, genetic and selective parameters can be fine-tuned in QuantiNemo 2: population, selection, trait(s) architecture, genetic map for QTL and/or markers, environment, demography and mating system are the main features.

AVAILABILITY AND IMPLEMENTATION:

QuantiNemo 2 is a C++ program with a source code available under the GNU General Public License version 3. Executables are provided for Windows, MacOS and Linux platforms, together with a comprehensive manual and tutorials illustrating its flexibility. The executable, manual and tutorial can be found on the website www2.unil.ch/popgen/softwares/quantinemo/, while the source code and user support are given through GitHub: github.com/jgx65/quantinemo.

SUPPLEMENTARY INFORMATION:

Supplementary data are available at Bioinformatics online.

Supplemental Content

Full text links

Icon for Silverchair Information Systems Icon for PubMed Central
Loading ...
Support Center