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Urology. 2019 Feb 23. pii: S0090-4295(19)30173-6. doi: 10.1016/j.urology.2019.02.015. [Epub ahead of print]

The Natural History of Wilms Tumor-A Case Comparison of Two Different Tumors.

Author information

1
Department of Surgery, Division of Urology, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO. Electronic address: jonathan.walker@childrenscolorado.org.
2
Department of Radiology, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO.
3
Department of Surgery, Division of Urology, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO.

Abstract

Due to the rarity of Wilms tumor (WT) and the relative urgency with which pediatric renal tumors are treated, there is little reported data on the natural history and growth of WTs. Historical reports of estimated doubling times of WTs were based on time to disease recurrence after initial diagnosis and treatment, and were published before the current advancements in molecular biomarker testing. We compare 2 cases of WT with sequential imaging, and postulate how the growth parameters of these tumors may be associated with differing chromosomal traits.

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