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Nat Commun. 2019 Feb 1;10(1):551. doi: 10.1038/s41467-018-08272-w.

Patterns of genetic differentiation and the footprints of historical migrations in the Iberian Peninsula.

Author information

1
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
2
Fundación Pública Galega de Medicina Xenómica- CIBERER-IDIS, Santiago de Compostela, A Coruña, Spain.
3
Grupo de Medicina Xenómica, Centro Nacional de Genotipado (CEGEN-PRB2-ISCIII), Universidade de Santiago de Compostela, A Coruña, Spain.
4
Institute of Forensic Sciences., University of Santiago de Compostela, A Coruña, Spain.
5
Department of Statistics, University of Oxford, Oxford, OX1 3LB, UK.
6
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK. myers@stats.ox.ac.uk.
7
Department of Statistics, University of Oxford, Oxford, OX1 3LB, UK. myers@stats.ox.ac.uk.

Abstract

The Iberian Peninsula is linguistically diverse and has a complex demographic history, including a centuries-long period of Muslim rule. Here, we study the fine-scale genetic structure of its population, and the genetic impacts of historical events, leveraging powerful, haplotype-based statistical methods to analyse 1413 individuals from across Spain. We detect extensive fine-scale population structure at extremely fine scales (below 10 Km) in some regions, including Galicia. We identify a major east-west axis of genetic differentiation, and evidence of historical north to south population movement. We find regionally varying fractions of north-west African ancestry (0-11%) in modern-day Iberians, related to an admixture event involving European-like and north-west African-like source populations. We date this event to 860-1120 CE, implying greater genetic impacts in the early half of Muslim rule in Iberia. Together, our results indicate clear genetic impacts of population movements associated with both the Muslim conquest and the subsequent Reconquista.

PMID:
30710075
PMCID:
PMC6358624
DOI:
10.1038/s41467-018-08272-w
[Indexed for MEDLINE]
Free PMC Article

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